Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 16/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4445433 | 0.99 | NSD2 (1.00) | NSD2LMNACA1CA2CA9 | |
| SCHEMBL4450802 | 0.90 | NSD2 (0.82) | NSD2CA1CA2CA9 | |
| SCHEMBL4448428 | 0.89 | NSD2 (0.80) | NSD2LMNA | |
| Hydrochloric Acid SCHEMBL4445018 | 0.89 | NSD2 (0.82) | NSD2CA1CA2CA9 | |
| SCHEMBL4441197 | 0.88 | NSD2 (1.00) | NSD2 | |
| SCHEMBL4453024 | 0.88 | NSD2 (0.78) | NSD2 | |
| Hydrochloric Acid SCHEMBL4444943 | 0.88 | NSD2 (0.81) | NSD2 | |
| SCHEMBL4454417 | 0.87 | NSD2 (0.78) | NSD2 | |
| SCHEMBL4443335 | 0.87 | NSD2 (0.78) | NSD2 | |
| Hydrochloric Acid SCHEMBL4441215 | 0.87 | NSD2 (0.79) | NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |