Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444373 | 0.87 | — | — | |
| SCHEMBL2328444 | 0.87 | — | — | |
| SCHEMBL132643 | 0.87 | — | — | |
| Acetic Acid SCHEMBL3888013 | 0.85 | OR51E2 (0.50) | OR51E2 | |
| Choline SCHEMBL28382974 | 0.85 | MEN1 (0.40) | OR51E2 | |
| Ethylene Glycol SCHEMBL29006093 | 0.82 | OR51E2 (0.39) | OR51E2 | |
| Methacrylic Acid SCHEMBL10932249 | 0.77 | OR51E2 (0.42) | OR51E2 | |
| Dimethyl Sulfoxide SCHEMBL9985876 | 0.76 | OR51E2 (0.35) | OR51E2 | |
| Phosphocholine SCHEMBL10588190 | 0.76 | SMN1; SMN2 (0.46) | PGK1PGK2 | |
| Acrylic Acid SCHEMBL4814346 | 0.76 | LMNA (0.42) | OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831794-A4 | ACYCLOVIR DERIVATIVES FOR TOPICAL USE | HOSTETLER KARL Y (US) | 1998-11-04 | — | — | EP | disclosed |
| US-5756116-A | VIRICIDES USING ACYCLOVIR RESISTANT STRAIN OF HERPES VIRUS | HOSTETLER KARL Y (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0831794-A1 | ACYCLOVIR DERIVATIVES FOR TOPICAL USE | HOSTETLER, Karl Y. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040088-A1 | ACYCLOVIR DERIVATIVES FOR TOPICAL USE | HOSTETLER KARL Y (US) | 1996-12-19 | — | — | WO | disclosed |