SCHEMBL4443797

SCHEMBL4443797

C=C(CC(C(C)=O)C(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.54
TET3 O43151 1/20 0.54
TET1 Q8NFU7 1/20 0.54
GRIK1 P39086 3/20 0.52
GRIK2 Q13002 2/20 0.52
GRM1 Q13255 1/20 0.52
GRM2 Q14416 1/20 0.52
TGFBR1 P36897 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11037132 0.85 TET2 (0.64) TET2TET3TET1GRIK1GRIK2
SCHEMBL4144935 0.80 GRN (0.36) TET2TET3TET1GRIK1GRIK2
SCHEMBL11919740 0.75 GRIK1 (0.37) TET2TET3TET1GRIK1GRIK2
SCHEMBL2045388 0.74 TDP1 (0.48) ALOX15
SCHEMBL4623050 0.74 TDP1 (0.35) GRIK1ALOX15
SCHEMBL8909192 0.74 TDP1 (0.48) ALOX15
SCHEMBL11309347 0.74 TDP1 (0.48) GRIK1
Acetone SCHEMBL23040790 0.73 TET2 (0.56) TET2TET3TET1GRIK1GRIK2
SCHEMBL3045176 0.73 TET2 (0.56) TET2TET3TET1GRIK1GRIK2
Acetic Acid SCHEMBL10488044 0.73 TET2 (0.50) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1256611-B1 Aqueous dispersion and coated product JSR CORP (JP) 2009-07-29 EP disclosed
US-6953821-B2 Aqueous dispersion, process for production thereof and coated substances JSR CORPORATION (JP) 2005-10-11 US disclosed
US-6726997-B2 WWATERPROOF, HARDNESS, RATION TRANSPARENT; PROTECTIVE COATINGS JSR CORPORATION (JP) 2004-04-27 US disclosed
US-20030073779-A1 Aqueous dispersion and coated product JSR CORPORATION (JP) 2003-04-17 US disclosed
US-20030045626-A1 Aqueous dispersion, process for production thereof and coated substances JSR CORPORATION (JP) 2003-03-06 US disclosed
EP-1256611-A2 Aqueous dispersion and coated product JSR Corporation (JP) 2002-11-13 EP disclosed
EP-1172412-A1 AQUEOUS DISPERSION, PROCESS FOR PRODUCTION THEREOF AND COATED SUBSTANCES JSR Corporation (JP) 2002-01-16 EP disclosed
US-3962172-A GLASS FIBER REINFORCED POLYAMIDE MOLDING MATERIAL OF HIGH IMPACT STRENGTH BASF AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed