SCHEMBL2045388

SCHEMBL2045388

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nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.46
SLC22A6 Q4U2R8 1/20 0.43
FOLH1 Q04609 2/20 0.39
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
BHMT Q93088 1/20 0.36
GABRR1 P24046 2/20 0.36
LMNA P02545 1/20 0.36
FFAR3 O14843 1/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8909192 1.00 TDP1 (0.48) TDP1SMN1; SMN2SLC22A6FOLH1MAPT
SCHEMBL28422790 0.97 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6FOLH1MAPT
SCHEMBL517199 0.91 SLC22A6 (0.45) TDP1SMN1; SMN2SLC22A6MAPTALOX15
SCHEMBL9517361 0.86 TDP1 (0.37) TDP1SMN1; SMN2SLC22A6FOLH1BHMT
Succinic Acid SCHEMBL30420896 0.83 LMNA (0.50) TDP1SMN1; SMN2SLC22A6FOLH1LMNA
SCHEMBL11309347 0.82 TDP1 (0.48) TDP1SMN1; SMN2LMNAFFAR3ALDH1A1
SCHEMBL4623050 0.82 TDP1 (0.35) TDP1SMN1; SMN2FOLH1MAPTALOX15
Ethylenediamine SCHEMBL29025807 0.81 GABRR1 (0.42) TDP1SMN1; SMN2SLC22A6ALOX15BHMT
SCHEMBL1702651 0.81 SLC22A6 (0.38) TDP1SMN1; SMN2SLC22A6MAPTALOX15
SCHEMBL9789924 0.81 SLC22A6 (0.38) TDP1SMN1; SMN2SLC22A6MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600809-B2 Ethylene-vinyl alcohol copolymer composition, and preparation method therefor CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2026-04-14 US claimed
EP-4294981-B1 PAPER MATERIAL FOR FLUID CONTAINERS HAVING CHARACTERISTICS OF CALIBRATED FRAGILITY AND RIGIDITY AND A BARRIER PROPERTY FEDRIGONI SPA (IT) 2025-11-26 EP claimed
CN-111748077-B Alkali-soluble resin, hydrogenated compound, method for producing same, resin composition, cured film thereof, touch panel, and optical filter 日铁化学材料株式会社 2025-04-18 CN claimed
CN-116601223-B Ethylene-vinyl alcohol copolymer composition and method for preparing the same 中国石油化工股份有限公司 2025-03-28 CN claimed
CN-116144029-B Organosilicon leveling agent, preparation method thereof, black matrix photosensitive resin composition, color filter and liquid crystal display device 阜阳欣奕华新材料科技股份有限公司 2025-03-18 CN claimed
US-20250075431-A1 PAPER MATERIAL WITH VIRUCIDAL, BIOCIDAL AND BARRIER PROPERTIES TO WATER, FATS AND OILS FEDRIGONI S.P.A. (IT) 2025-03-06 US claimed
US-20250067001-A1 PAPER MATERIAL WITH TOTAL CLOSURE PARTICULARLY FOR USE IN THE FOOD INDUSTRY FEDRIGONI S.P.A. (IT) 2025-02-27 US claimed
EP-4457400-A1 PAPER MATERIAL WITH VIRUCIDAL, BIOCIDAL AND BARRIER PROPERTIES TO WATER, FATS AND OILS FEDRIGONI S.P.A. (IT) 2024-11-06 EP claimed
EP-4457398-A1 PAPER MATERIAL WITH TOTAL CLOSURE PARTICULARLY FOR USE IN THE FOOD INDUSTRY FEDRIGONI S.P.A. (IT) 2024-11-06 EP claimed
CN-118755080-A Preparation method of polyamide 66 with high strength and high elongation at break 江苏扬农化工集团有限公司 2024-10-11 CN claimed
WO-2016053877-A1 FREE-RADICAL POLYMERIZATION METHODS AND ARTICLES THEREBY 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-04-07 WO claimed
EP-0912467-B1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE SA (FR) 2002-04-24 EP claimed
EP-0912467-A1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE (FR) 1999-05-06 EP claimed
WO-1998000375-A1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE (FR) 1998-01-08 WO claimed
EP-0303853-B1 POLYMER BLENDS HAVING REVERSE PHASE MORPHOLOGY FOR CONTROLLED DELIVERY OF BIOACTIVE AGENTS EASTMAN CHEMICAL COMPANY (US) 1993-09-22 EP claimed
EP-0401532-B1 PROCESS FOR THE PREPARATION OF A STORAGE STABLE LEVULINIC ACID Chemie Linz Gesellschaft m.b.H. (AT) 1993-03-24 EP claimed
US-5189215-A Treating mixture of acetylsuccinate and aqueous mineral acid with steam in countercurrent in reactor cascade above boiling point of alcohol or azeotrope formed CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1993-02-23 US claimed
EP-0279277-B1 WATER SOLUBLE MONOAZO-PYRAZOLONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-06 EP claimed
EP-0401532-A1 Process for the preparation of a storage stable levulinic acid Chemie Linz Gesellschaft m.b.H. (AT) 1990-12-12 EP claimed
US-4013625-A Process for the linearization of polyurethanes with lactams and lactam addition compounds BAYER AKTIENGESELLSCHAFT (DT) 1977-03-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600809-B2 Ethylene-vinyl alcohol copolymer composition, and preparation method therefor ASIC1, ADH1A, ATP6V1H TDP1 4217/4885SMN1; SMN2 1911/4885SLC22A6 988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.