SCHEMBL444399

SCHEMBL444399

[C]1=CNOc2ccccc21

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1598834 0.67
SCHEMBL2987748 0.64 ALOX5 (0.30) ALOX5
SCHEMBL1116430 0.62
SCHEMBL122449 0.60
SCHEMBL996383 0.60
SCHEMBL276860 0.59 ABCG2 (0.39)
SCHEMBL23727987 0.59
SCHEMBL29469952 0.58 MAPT (0.33)
SCHEMBL11566149 0.58 TRPA1 (0.41) ALOX5
SCHEMBL29924552 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103224488-A Heterocyclic compound or salt thereof OTSUKA PHARMA CO LTD 2013-07-31 CN claimed
CN-103140221-A Novel heterocyclic derivatives and pharmaceutical composition containing same SHIONOGI & CO 2013-06-05 CN claimed
CN-103003246-A Benzocycloalkenes as antifungal agents BAYER CROPSCIENCE AG 2013-03-27 CN claimed
CN-102933590-A Fungicide n-[(trisubstitutedsilyl)methyl]-carboxamide derivatives BAYER CROPSCIENCE AG 2013-02-13 CN claimed
CN-101248044-B Indole compounds FOURNIER LAB SA 2012-05-30 CN claimed
CN-101821256-A Novel heterocyclic compounds as mGlu5 antagonists RECORDATI IRELAND LTD 2010-09-01 CN claimed
WO-2010077740-A2 NOVEL ANTIVIRAL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE CYTOKINE PHARMASCIENCES, INC. (US) 2010-07-08 WO claimed
CN-101605779-A Arylprop acid amides, aryl acrylamide, arylprop alkynyl amide or arylmethyl urea analogue as plasma thromboplastin antecedent A inhibitor BRISTOL MYERS SQUIBB CO (US) 2009-12-16 CN claimed
CN-101489555-A Nf-kappa OTSUKA PHARMA CO LTD (JP) 2009-07-22 CN claimed
CN-101484442-A Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia ASTRAZENECA AB (SE) 2009-07-15 CN claimed
CN-1566096-A Prostaglandin agonists and their use to treat bonedisorders PFIZER (US) 2005-01-19 CN claimed
CN-1404480-A Pyrimidine carboxamides as inhibitors of the PDE4 isozyme PFIZER PROD INC (US) 2003-03-19 CN claimed
CN-1074413-C Novel benzimidazole derivatives having CGMP-phosphodisterase inhibiting activity OTSUKA PHARMA CO LTD (JP) 2001-11-07 CN claimed
CN-1070856-C Thiazole derivatives OTSUDA PHARMACEUTICAL CO LTD (JP) 2001-09-12 CN claimed
CN-1275123-A Prostaglandin agonists and their use to treat bone disorders PFIZER (US) 2000-11-29 CN claimed
EP-0570006-B1 A silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1999-03-24 EP claimed
CN-1198160-A Thiazole derivative OTSUKA PHARMA CO LTD (JP) 1998-11-04 CN claimed
CN-1158129-A Novel benzimidazole derivatives having CGMP-phosphodisterase inhibiting activity OTSUKA PHARMA CO LTD (JP) 1997-08-27 CN claimed
US-5362617-A Multilayer element of support with color couplers FUJI PHOTO FILM CO., LTD. (JP) 1994-11-08 US claimed
EP-0570006-A1 A silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-11-18 EP claimed