Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8480733 | 0.76 | KDM4E (0.36) | TRPA1 | |
| SCHEMBL29757278 | 0.76 | KDM4E (0.36) | TRPA1 | |
| Urea SCHEMBL8887498 | 0.69 | KDM4E (0.35) | TRPA1 | |
| Oxalic Acid SCHEMBL10499933 | 0.69 | MEN1 (0.32) | — | |
| Acetic Acid SCHEMBL25341096 | 0.68 | TRPA1 (0.31) | TRPA1 | |
| Fumaric Acid SCHEMBL11602682 | 0.66 | ALDH1A1 (0.38) | — | |
| SCHEMBL218834 | 0.64 | TRPA1 (0.36) | TRPA1 | |
| SCHEMBL6118600 | 0.63 | — | — | |
| SCHEMBL23400 | 0.62 | KDM4E (0.35) | TRPA1 | |
| SCHEMBL209689 | 0.62 | TRPA1 (0.34) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3642202-A1 | DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | Pfizer Inc (US) | 2020-04-29 | — | — | EP | claimed |
| EP-3478679-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES FOR TREATING NEUROLOGICAL AND NEURODEGENERATIVE DISEASES | Pfizer Inc (US) | 2019-05-08 | — | — | EP | claimed |
| EP-3419979-A1 | 6,7-DIHYDRO-5H-PYRAZOLO[5,1-B][1,3]OXAZINE-2-CARBOXAMIDE COMPOUNDS | Pfizer Inc (US) | 2019-01-02 | — | — | EP | claimed |
| WO-2018234953-A1 | DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER INC. (US) | 2018-12-27 | — | — | WO | claimed |
| EP-3310784-A1 | TRICYCLIC COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | Pfizer Inc (US) | 2018-04-25 | — | — | EP | claimed |
| WO-2018002760-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES FOR TREATING NEUROLOGICAL AND NEURODEGENERATIVE DISEASES | PFIZER INC. (US) | 2018-01-04 | — | — | WO | claimed |
| WO-2017145013-A1 | 6,7-DIHYDRO-5H-PYRAZOLO[5,1-B][1,3]OXAZINE-2-CARBOXAMIDE COMPOUNDS | PFIZER INC. (US) | 2017-08-31 | — | — | WO | claimed |
| EP-3177624-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | Pfizer Inc (US) | 2017-06-14 | — | — | EP | claimed |
| WO-2016203347-A1 | TRICYCLIC COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | PFIZER INC. (US) | 2016-12-22 | — | — | WO | claimed |
| WO-2016020786-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | PFIZER INC. (US) | 2016-02-11 | — | — | WO | claimed |
| CN-1074413-C | Novel benzimidazole derivatives having CGMP-phosphodisterase inhibiting activity | OTSUKA PHARMA CO LTD (JP) | 2001-11-07 | — | — | CN | claimed |
| CN-1070856-C | Thiazole derivatives | OTSUDA PHARMACEUTICAL CO LTD (JP) | 2001-09-12 | — | — | CN | claimed |
| CN-1275123-A | Prostaglandin agonists and their use to treat bone disorders | PFIZER (US) | 2000-11-29 | — | — | CN | claimed |
| EP-0570006-B1 | A silver halide photographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 1999-03-24 | — | — | EP | claimed |
| CN-1198160-A | Thiazole derivative | OTSUKA PHARMA CO LTD (JP) | 1998-11-04 | — | — | CN | claimed |
| EP-0858452-A1 | THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | claimed |
| WO-1998004536-A1 | THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1998-02-05 | — | — | WO | claimed |
| CN-1158129-A | Novel benzimidazole derivatives having CGMP-phosphodisterase inhibiting activity | OTSUKA PHARMA CO LTD (JP) | 1997-08-27 | — | — | CN | claimed |
| US-5362617-A | Multilayer element of support with color couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-08 | — | — | US | claimed |
| EP-0570006-A1 | A silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-11-18 | — | — | EP | claimed |