SCHEMBL218834

SCHEMBL218834

C1=NOc2ccccc2-c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.36
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
HSP90AA1 P07900 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL8887503 0.89 TRPA1 (0.40) TRPA1MAPK1ATMHSP90AA1
SCHEMBL11830486 0.89 TRPA1 (0.35) TRPA1KDM4EMAPK1ATMHSP90AA1
SCHEMBL9268163 0.86 TRPA1 (0.38) TRPA1ATMCYP1A2CYP2D6
SCHEMBL5944362 0.71 ALDH1A1 (0.44) TRPA1KDM4E
SCHEMBL8538005 0.71 NPC1 (0.36) KDM4EMAPK1ATM
SCHEMBL4501496 0.68 TYMS (0.35) TRPA1KDM4EMAPK1ATMCYP1A2
SCHEMBL10483802 0.66 MYC (0.42) KDM4E
SCHEMBL5841466 0.65 DRD2 (0.37) TRPA1KDM4EMAPK1ATMHSP90AA1
SCHEMBL244606 0.65 KDM4E (0.37) TRPA1KDM4E
SCHEMBL29757278 0.64 KDM4E (0.36) TRPA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1668 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026042047-A1 COMPOSITIONS AND ARTICLES COMPRISING REVERSIBLE COMPLEXES OF CROSSLINKED CARRAGEENAN JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-02-26 WO claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-120025756-A Degradable printing adhesive tape and preparation method thereof 浙江睿麟科技有限公司 2025-05-23 CN claimed
CN-222342036-U Dibenzoxazelone heterocyclic derivative preparation device 江苏兢业制药有限公司 2025-01-14 CN claimed
US-20240277729-A1 METHODS OF TREATMENT AND PHARMACEUTICAL COMPOSITIONS USING AN SGLT-2 INHIBITOR AND A NEUROLEPTIC AGENT BOEHRINGER INGELHEIM INT (DE) 2024-08-22 US claimed
CN-117343094-A Light-emitting element and nitrogen-containing compound for light-emitting element 三星显示有限公司 2024-01-05 CN claimed
CN-116854643-A Synthesis method of dibenzodiazepine or oxyazepine compound 中山大学 2023-10-10 CN claimed
CN-114752508-B Aspergillus polypolypolyvidone MNP-2 and application thereof in synthesis of dibenzooxazepine compounds 浙江工业大学 2023-09-05 CN claimed
US-11717532-B2 Methods and compositions for treating wounds utilizing chitosan compounds SYNEDGEN, INC. (US) 2023-08-08 US claimed
CN-113072518-B Dibenzo azepine derivative and preparation method thereof 上海兆维科技发展有限公司 2022-10-21 CN claimed
EP-0386117-A1 TREATING PREMENSTRUAL OR LATE LUTEAL PHASE SYNDROME MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-09-12 EP claimed
WO-1990004387-A2 COMPOSITIONS FOR TREATING TOBACCO WITHDRAWAL SYMPTOMS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-05-03 WO claimed
US-4886795-A Treatment and prevention of retinal edema with dopaminergic antagonists SCHACHAR RONALD A (US) 1989-12-12 US claimed
WO-1989003692-A1 TREATING PREMENSTRUAL OR LATE LUTEAL PHASE SYNDROME MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1989-05-05 WO claimed
EP-0040860-B1 DIBENZOXAZEPINE DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME Chugai Seiyaku Kabushiki Kaisha (JP) 1984-03-14 EP claimed
US-4435391-A ANTICOAGULANTS, ANTILIPEMIC AGENTS, 6- OR 8-CARBOXY SUBSTITUTED CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1984-03-06 US claimed
EP-0012385-B1 DIBENZ(B,F)(1,4)OXAZEPINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS Chugai Seiyaku Kabushiki Kaisha (JP) 1983-02-16 EP claimed
EP-0040860-A1 Dibenzoxazepine derivative, process for preparing the same and pharmaceutical composition comprising the same Chugai Seiyaku Kabushiki Kaisha (JP) 1981-12-02 EP claimed
US-4290953-A ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT AND ANTICOAGULANT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1981-09-22 US claimed
EP-0012385-A1 Dibenz(b,f)(1,4)oxazepine derivatives, process for their preparation and pharmaceutical compositions Chugai Seiyaku Kabushiki Kaisha (JP) 1980-06-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277729-A1 METHODS OF TREATMENT AND PHARMACEUTICAL COMPOSITIONS USING AN SGLT-2 INHIBITOR AND A NEUROLEPTIC AGENT SLC5A2, SLC5A1, SLC6A2 TRPA1 2274/4885KDM4E 2651/4885MAPK1 1767/4885
US-11717532-B2 Methods and compositions for treating wounds utilizing chitosan compounds CHIA, MMP8, CHIT1 TRPA1 1546/4885KDM4E 3991/4885MAPK1 3263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.