Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178286 | 0.79 | ALDH1A1 (0.47) | ALDH1A1CYP1A2HIF1ATP53MAPT | |
| SCHEMBL11759184 | 0.71 | ALDH1A1 (0.47) | ALDH1A1CYP1A2HIF1ATP53MAPT | |
| SCHEMBL1044726 | 0.71 | — | — | |
| SCHEMBL4120017 | 0.68 | HIF1A (0.53) | ALDH1A1CYP1A2HIF1ATP53MAPT | |
| SCHEMBL5179051 | 0.68 | TP53 (0.54) | ALDH1A1CYP1A2HIF1ATP53MAPT | |
| SCHEMBL4451164 | 0.67 | ALOX15 (0.52) | ALDH1A1CYP1A2HIF1ATP53MAPT | |
| SCHEMBL5177864 | 0.67 | TP53 (0.45) | ALDH1A1CYP1A2HIF1ATP53MAPT | |
| SCHEMBL4442531 | 0.66 | TP53 (0.55) | ALDH1A1CYP1A2HIF1ATP53MAPT | |
| SCHEMBL5179413 | 0.64 | TP53 (0.58) | ALDH1A1CYP1A2HIF1ATP53ALOX15 | |
| SCHEMBL5178494 | 0.63 | TP53 (0.56) | ALDH1A1CYP1A2HIF1ATP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501539-B2 | Process for the preparation of alkylidenecyclopentanone derivatives | FIRMENICH SA (CH) | 2009-03-10 | — | — | US | disclosed |
| US-20050187299-A1 | Process for the preparation of alkylidenecyclopentanone derivatives | FIRMENICH S.A. (CH) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187299-A1 | Process for the preparation of alkylidenecyclopentanone derivatives | CYP1B1, AKR1C3, CYP1A1 | ALDH1A1 99/4885CYP1A2 13/4885HIF1A 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.