Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.62 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442605 | 0.98 | CHRM1 (0.59) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL8883635 | 0.91 | PGR (0.56) | CHRM1CHRM2CHRM4CHRM3OPRM1 | |
| SCHEMBL4939509 | 0.90 | CHRM1 (0.74) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL606455 | 0.88 | CHRM1 (0.53) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL606454 | 0.88 | CHRM1 (0.53) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL4302535 | 0.88 | CHRM1 (0.53) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL20358063 | 0.87 | OPRM1 (0.55) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL607529 | 0.87 | CHRM1 (0.53) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL607530 | 0.87 | CHRM1 (0.53) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL4541065 | 0.84 | HSD11B1 (0.56) | CHRM1CHRM2CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124883-A1 | NOVEL 1,3-DIHYDRO-BENZOIMIDAZOL-2-ONES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009124883-A1 | NOVEL 1,3-DIHYDRO-BENZOIMIDAZOL-2-ONES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-10-15 | — | — | WO | disclosed |