Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3582986 | 1.00 | REN (0.35) | RENFFAR4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3594918 | 0.86 | GRM2 (0.35) | RENFFAR4LMNA | |
| SCHEMBL3592444 | 0.83 | ALDH1A1 (0.37) | FFAR4ALDH1A1LMNA | |
| SCHEMBL3597465 | 0.81 | LMNA (0.37) | NPC1RAB9ASMN1; SMN2L3MBTL1GRM5 | |
| SCHEMBL3593019 | 0.77 | GRM2 (0.38) | RENNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3593066 | 0.74 | SOAT1 (0.41) | RENALDH1A1 | |
| SCHEMBL3587336 | 0.72 | STING1 (0.35) | GRM5LMNA | |
| SCHEMBL3592419 | 0.70 | ALDH1A1 (0.34) | ALDH1A1LMNA | |
| SCHEMBL3581823 | 0.69 | MDM2 (0.39) | — | |
| SCHEMBL3589624 | 0.67 | LMNA (0.38) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |