Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832310 | 0.93 | THRA (0.45) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL6855098 | 0.91 | THRA (0.47) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL11370128 | 0.86 | THRA (0.55) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL4443929 | 0.85 | PTGS2 (0.50) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL6745885 | 0.85 | PTGS2 (0.50) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL4454133 | 0.85 | PTGS2 (0.50) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL4446465 | 0.85 | PTGS2 (0.50) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL6743239 | 0.85 | PTGS2 (0.50) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL1965860 | 0.85 | PTGS2 (0.50) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL941553 | 0.83 | THRA (0.58) | THRATHRBLIPGPTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090027586-A1 | Thermoplastic Resin Composition, and Liquid Crystal Display Component Thereof or Information Recording Media Component Thereof | POLYPLASTICS CO., LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1992666-A1 | THERMOPLASTIC RESIN COMPOSITION AND LIQUID CRYSTAL DISPLAY PART OR INFORMATION RECORDING MEDIUM PART USING THE COMPOSITION | Polyplastics Co., Ltd. (JP) | 2008-11-19 | — | — | EP | disclosed |