Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4446465 | 0.95 | PTGS2 (0.50) | THRATHRBPTGS2ALOX5LTB4R | |
| SCHEMBL4454133 | 0.95 | PTGS2 (0.50) | THRATHRBPTGS2ALOX5LTB4R | |
| SCHEMBL6743239 | 0.95 | PTGS2 (0.50) | THRATHRBPTGS2ALOX5LTB4R | |
| SCHEMBL4443929 | 0.95 | PTGS2 (0.50) | THRATHRBPTGS2ALOX5LTB4R | |
| SCHEMBL6745885 | 0.95 | PTGS2 (0.50) | THRATHRBPTGS2ALOX5LTB4R | |
| SCHEMBL1965860 | 0.95 | PTGS2 (0.50) | THRATHRBPTGS2ALOX5LTB4R | |
| SCHEMBL4444324 | 0.91 | THRA (0.54) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL6742752 | 0.89 | PTGS2 (0.45) | THRATHRBPTGS2ALOX5LTB4R | |
| SCHEMBL28473665 | 0.86 | PTGS2 (0.44) | THRATHRBPTGS2ALOX5LTB4R | |
| SCHEMBL10832310 | 0.84 | THRA (0.45) | THRATHRBPTGS2ALOX5PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784226-B2 | COMPOUNDING STYRENIC RESIN WITH GREATER THAN 2 WT % WATER AND ANTIOXIDANT PREPARED BY BLENDING ORGANIC PHOSPHITE OR PHOSPHONITE WITH ACID-BINDING METAL SALT TREATED WITH SURFACE CONDITIONING AGENT | CHI MEI CORPORATION (TW) | 2004-08-31 | — | — | US | disclosed |
| US-20030114559-A1 | Process for producing a styrenic resin composition | CHI MEI CORPORATION | 2003-06-19 | — | — | US | disclosed |
| US-20020002222-A1 | PHOSPHORUS-CONTAINING ANTIOXIDANT STABILIZED AGAINST HYDROLYSIS | CHI MEI CORPORATION (TW) | 2002-01-03 | — | — | US | disclosed |
| US-4305839-A | PHOSPHITES AND PHOSPHONITES FOR COLOR STABILITY | CARSTAB CORPORATION (US) | 1981-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002222-A1 | PHOSPHORUS-CONTAINING ANTIOXIDANT STABILIZED AGAINST HYDROLYSIS | LPO, GPX4, GPX1 | THRA 3787/4885THRB 4079/4885PTGS2 2332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.