Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4171821 | 0.80 | CCR2 (0.38) | — | |
| Trifluoroacetic Acid SCHEMBL4166172 | 0.79 | SIRT2 (0.41) | HDAC1OPRK1FAAHCES1 | |
| Trifluoroacetic Acid SCHEMBL4166154 | 0.76 | SIRT2 (0.38) | HDAC1OPRK1FAAHCES1 | |
| Trifluoroacetic Acid SCHEMBL4165163 | 0.76 | SIRT2 (0.38) | HDAC1OPRK1CES1 | |
| Trifluoroacetic Acid SCHEMBL4150080 | 0.75 | CES1 (0.43) | HDAC1CES1 | |
| Trifluoroacetic Acid SCHEMBL4162623 | 0.75 | SIRT2 (0.38) | HDAC1OPRK1CES1 | |
| Trifluoroacetic Acid SCHEMBL4156590 | 0.74 | SIRT2 (0.41) | HDAC1OPRK1CES1 | |
| Trifluoroacetic Acid SCHEMBL4149911 | 0.73 | SIRT2 (0.35) | HDAC1OPRK1CES1 | |
| Trifluoroacetic Acid SCHEMBL4154033 | 0.72 | CYP1A2 (0.39) | TP53 | |
| SCHEMBL4163608 | 0.71 | CES1 (0.54) | HDAC1FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | HDAC1 2/4885CAPN1 1797/4885OPRK1 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.