Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444779 | 1.00 | HTT (0.51) | HTTL3MBTL1TP53GAAMAPT | |
| SCHEMBL17126990 | 0.81 | HCAR2 (0.43) | L3MBTL1GAAMAPTNPSR1ALDH1A1 | |
| SCHEMBL27726560 | 0.81 | TP53 (0.44) | HTTL3MBTL1TP53MAPTNPSR1 | |
| SCHEMBL13393848 | 0.81 | TP53 (0.44) | HTTL3MBTL1TP53MAPTNPSR1 | |
| SCHEMBL18828565 | 0.81 | HCAR2 (0.52) | L3MBTL1MAPTNPSR1ALDH1A1HCAR2 | |
| SCHEMBL7512242 | 0.81 | HCAR2 (0.52) | L3MBTL1MAPTNPSR1ALDH1A1HCAR2 | |
| SCHEMBL7512241 | 0.81 | HCAR2 (0.52) | L3MBTL1MAPTNPSR1ALDH1A1HCAR2 | |
| SCHEMBL13886420 | 0.79 | TP53 (0.43) | HTTL3MBTL1TP53MAPTNPSR1 | |
| SCHEMBL27747318 | 0.79 | TP53 (0.43) | HTTL3MBTL1TP53MAPTNPSR1 | |
| SCHEMBL10073830 | 0.79 | HCAR2 (0.47) | L3MBTL1MAPTNPSR1ALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111993-A1 | Process for Preparing Beta-(Fluorophenyl)-Propanoate Ester Derivatives | ASTRAZENECA AB (SE) | 2009-04-30 | — | — | US | disclosed |
| EP-1951652-A1 | PROCESS FOR PREPARING BETA- (FLUOROPHENYL) -PROPANOATE ESTER DERIVATIVES | Astra Zeneca AB (SE) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007057643-A1 | PROCESS FOR PREPARING BETA- (FLUOROPHENYL) -PROPANOATE ESTER DERIVATIVES | ASTRAZENECA AB (SE) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111993-A1 | Process for Preparing Beta-(Fluorophenyl)-Propanoate Ester Derivatives | ADH1A, ADH1C, ADH5 | HTT 4820/4885L3MBTL1 4831/4885TP53 4184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.