SCHEMBL4444811

SCHEMBL4444811

c1ccc2c(-c3ccc4ccc5ccccc5c4c3)cccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
HSD17B10 Q99714 4/20 0.56
HIF1A Q16665 2/20 0.56
CYP1B1 Q16678 1/20 0.56
MCL1 Q07820 2/20 0.53
ACMSD Q8TDX5 1/20 0.53
TSHR P16473 2/20 0.52
CYP2A6 P11509 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CA12 O43570 3/20 0.49
CA1 P00915 3/20 0.49
CA2 P00918 3/20 0.49
CA9 Q16790 3/20 0.49
HPRT1 P00492 1/20 0.48
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HPGD P15428 2/20 0.47
CYP1A2 P05177 1/20 0.47
MAPK1 P28482 1/20 0.45
CASP1 P29466 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57214 0.98 MCL1 (0.54) ALDH1A1HSD17B10HIF1ACYP1B1MCL1
SCHEMBL57494 0.89 ALDH1A1 (0.54) ALDH1A1HSD17B10HIF1ACYP1B1MCL1
SCHEMBL31742566 0.89 MCL1 (0.54) ALDH1A1HSD17B10HIF1ACYP1B1MCL1
SCHEMBL1527420 0.88 ALDH1A1 (0.59) ALDH1A1HSD17B10HIF1ACYP1B1MCL1
SCHEMBL1373671 0.88 MCL1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1MCL1
SCHEMBL28336706 0.88 HPRT1 (0.56) ALDH1A1HSD17B10HIF1ACYP1B1MCL1
SCHEMBL20124391 0.87 MCL1 (0.53) MCL1ACMSDCA12CA1CA2
SCHEMBL30274189 0.87 GSTP1 (0.57) ALDH1A1HSD17B10MCL1ACMSDTSHR
SCHEMBL598962 0.87 GSTP1 (0.57) ALDH1A1HSD17B10MCL1ACMSDTSHR
SCHEMBL19200465 0.87 ALDH1A1 (0.47) ALDH1A1HSD17B10HIF1ACYP1B1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2009267378-A ORGANIC LIGHT-EMITTING ELEMENT CANON INC 2009-11-12 JP disclosed