Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.54 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28336706 | 0.98 | HPRT1 (0.56) | ALDH1A1HSD17B10HIF1ACYP1B1HPRT1 | |
| SCHEMBL31742566 | 0.91 | MCL1 (0.54) | ALDH1A1HSD17B10HIF1ACYP1B1MCL1 | |
| SCHEMBL4444809 | 0.90 | HPRT1 (0.56) | ALDH1A1HSD17B10HIF1ACYP1B1HPRT1 | |
| SCHEMBL19199467 | 0.89 | MCL1 (0.44) | ALDH1A1HSD17B10HIF1ACYP1B1HPRT1 | |
| SCHEMBL13706395 | 0.89 | CYP2A6 (0.47) | ALDH1A1HSD17B10HIF1ACYP1B1HPRT1 | |
| SCHEMBL598962 | 0.89 | GSTP1 (0.57) | ALDH1A1HSD17B10MCL1ACMSDTSHR | |
| SCHEMBL4444811 | 0.89 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HIF1ACYP1B1HPRT1 | |
| SCHEMBL30274189 | 0.89 | GSTP1 (0.57) | ALDH1A1HSD17B10MCL1ACMSDTSHR | |
| SCHEMBL1527419 | 0.88 | HPRT1 (0.54) | ALDH1A1HSD17B10HIF1ACYP1B1HPRT1 | |
| SCHEMBL25177116 | 0.88 | MCL1 (0.51) | ALDH1A1HSD17B10HIF1ACYP1B1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287506-B1 | PHENANTHRENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| EP-1797158-B1 | PHENANTHRENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-05-01 | — | — | EP | disclosed |
| EP-3287506-A1 | PHENANTHRENE DERIVATIVES | Merck Patent GmbH (DE) | 2018-02-28 | — | — | EP | disclosed |
| US-8129037-B2 | Phenanthrene derivative | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20090026919-A1 | PHENANTHRENE DERIVATIVE | MERCK PATEN GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2009-01-29 | — | — | US | disclosed |
| EP-1645610-A1 | Phenanthrene derivatives | Covion Organic Semiconductors GmbH (DE) | 2006-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090026919-A1 | PHENANTHRENE DERIVATIVE | LEF1, CRY1, WNT1 | ALDH1A1 262/4885HSD17B10 1291/4885HIF1A 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.