Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126056 | 0.94 | LMNA (0.42) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL1126854 | 0.81 | GFER (0.39) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL1126361 | 0.80 | MAPT (0.41) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL1127022 | 0.77 | MAPT (0.42) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL16500308 | 0.76 | PSEN1 (0.41) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL1126449 | 0.76 | MAPT (0.41) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL2231012 | 0.76 | MAPT (0.45) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL1127284 | 0.75 | MAPT (0.42) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL30234731 | 0.75 | MAPT (0.42) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL1127162 | 0.75 | MAPT (0.41) | ALDH1A1MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |