Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14919709 | 0.86 | EPHX1 (0.38) | EPHX1CA2SIGMAR1RENHPGD | |
| SCHEMBL4443535 | 0.85 | ACLY (0.35) | EPHX1CA2SIGMAR1RENHPGD | |
| SCHEMBL628815 | 0.80 | CYP1A2 (0.44) | EPHX1CA2SIGMAR1RENHPGD | |
| SCHEMBL628897 | 0.77 | SIGMAR1 (0.36) | EPHX1CA2SIGMAR1RENHPGD | |
| SCHEMBL1834640 | 0.75 | CYP1A2 (0.47) | EPHX1SIGMAR1REN | |
| SCHEMBL628520 | 0.75 | SIGMAR1 (0.34) | EPHX1CA2SIGMAR1REN | |
| SCHEMBL12077107 | 0.75 | SIGMAR1 (0.53) | CA2SIGMAR1REN | |
| SCHEMBL8397068 | 0.75 | CYP1A2 (0.35) | EPHX1CA2SIGMAR1REN | |
| SCHEMBL6565161 | 0.73 | PSEN1 (0.35) | CA2RENHPGD | |
| SCHEMBL4439668 | 0.72 | CYP1A2 (0.32) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137187-A1 | PYRAZOLO [1,5-A]PYRIMIDINES AS INHIBITORS OF STEAROYL-COA DESATURASE | Inovacia AB (SE) | 2009-12-30 | — | — | EP | disclosed |
| US-20080255153-A1 | New compounds | BIOVITRUM AB (PUBL) (SE) | 2008-10-16 | — | — | US | disclosed |
| WO-2008116898-A1 | PYRAZOLO [1,5-A]PYRIMIDINES AS INHIBITORS OF STEAROYL-COA DESATURASE | BIOVITRUM AB (PUBL) (SE) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255153-A1 | New compounds | SCD, SCD5, FADS2 | EPHX1 1600/4885CA2 2946/4885SIGMAR1 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.