Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447186 | 0.84 | HPGD (0.58) | HPGDALDH1A1MAPK1DRD2 | |
| SCHEMBL7332240 | 0.79 | ACE (0.42) | HPGDALDH1A1MAPK1 | |
| SCHEMBL7332252 | 0.79 | ACE (0.42) | HPGDALDH1A1MAPK1 | |
| SCHEMBL29373976 | 0.77 | TDP1 (0.50) | — | |
| SCHEMBL5841439 | 0.77 | TDP1 (0.50) | — | |
| SCHEMBL586406 | 0.77 | TDP1 (0.50) | — | |
| SCHEMBL4168183 | 0.77 | TDP1 (0.50) | — | |
| SCHEMBL13771640 | 0.76 | TDP1 (0.49) | — | |
| SCHEMBL17019828 | 0.76 | — | — | |
| SCHEMBL7329451 | 0.75 | TDP1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086835-A1 | NOVEL CYANOGUANIDINES | TOPOTARGET A/S (DK) | 2009-07-16 | — | — | WO | disclosed |