Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445452 | 0.84 | HPGD (0.54) | HPGDALDH1A1MAPK1DRD2 | |
| SCHEMBL28431281 | 0.77 | HPGD (0.61) | HPGDALDH1A1MAPK1 | |
| SCHEMBL28431289 | 0.75 | HPGD (0.60) | HPGDALDH1A1MAPK1 | |
| SCHEMBL13771640 | 0.75 | TDP1 (0.49) | — | |
| SCHEMBL28432606 | 0.74 | HPGD (0.56) | HPGDALDH1A1MAPK1 | |
| SCHEMBL4457921 | 0.73 | HPGD (0.60) | HPGDALDH1A1MAPK1DRD2HTR1A | |
| SCHEMBL29263737 | 0.72 | HPGD (0.59) | HPGDALDH1A1MAPK1HTR1AHTR7 | |
| SCHEMBL28432509 | 0.72 | HPGD (0.56) | HPGDALDH1A1MAPK1 | |
| SCHEMBL28437659 | 0.72 | HPGD (0.56) | HPGDALDH1A1MAPK1HTR1AHTR7 | |
| SCHEMBL14450985 | 0.71 | ACHE (0.57) | HPGDALDH1A1MAPK1HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086835-A1 | NOVEL CYANOGUANIDINES | TOPOTARGET A/S (DK) | 2009-07-16 | — | — | WO | disclosed |