Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 4/20 | 0.31 |
| ▸ | PLD2 | O14939 | 1/20 | 0.30 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168227 | 0.88 | LMNA (0.34) | KMT2ACYP3A4CA1CA2CA9 | |
| SCHEMBL3595014 | 0.86 | NTRK1 (0.32) | CYP3A4CA1CA2CA9CCR5 | |
| SCHEMBL3592352 | 0.83 | ALDH1A1 (0.36) | KMT2ADRD2HTR7CCR5KCNH2 | |
| SCHEMBL3591176 | 0.74 | KCNN4 (0.36) | KCNN4 | |
| SCHEMBL3599584 | 0.73 | MAPK14 (0.37) | KMT2A | |
| Sulfamide SCHEMBL4438457 | 0.73 | CA1 (0.35) | KMT2AHTR2ANR1H2NR1H3CA1 | |
| SCHEMBL4441032 | 0.72 | DRD2 (0.41) | KMT2ADRD2HTR7CYP3A4 | |
| SCHEMBL3595202 | 0.72 | KMT2A (0.38) | KMT2AHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL4439801 | 0.72 | KMT2A (0.38) | KMT2AHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL3589557 | 0.72 | GRM5 (0.40) | KCNN4KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | claimed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | claimed |