⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831031 | 0.73 | — | — | |
| SCHEMBL5909 | 0.69 | — | — | |
| SCHEMBL27601131 | 0.67 | — | — | |
| SCHEMBL50602 | 0.65 | LMNA (0.40) | — | |
| Glycine SCHEMBL13739339 | 0.65 | — | — | |
| Glycine SCHEMBL29248317 | 0.65 | OR51E2 (0.83) | — | |
| Glycine SCHEMBL391786 | 0.63 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL3640989 | 0.63 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL2116443 | 0.63 | — | — | |
| Glycine SCHEMBL6675874 | 0.63 | GLRA1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065265-A1 | ALPHA-2-DELTA LIGANDS FOR NON-RESTORATIVE SLEEP | PFIZER INC. | 2012-03-15 | — | — | US | disclosed |
| US-20090069427-A1 | ALPHA-2-DELTA LIGANDS FOR NON-RESTORATIVE SLEEP | PFIZER INC. | 2009-03-12 | — | — | US | disclosed |
| EP-1993529-A1 | ALPHA-2-DELTA LIGANDS FOR NON-RESTORATIVE SLEEP | Pfizer Products Inc. (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007102058-A1 | ALPHA-2-DELTA LIGANDS FOR NON-RESTORATIVE SLEEP | PFIZER PRODUCTS INC. (US) | 2007-09-13 | — | — | WO | disclosed |