Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.83 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.83 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.83 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL13739339 | 1.00 | — | — | |
| Glycine SCHEMBL7030268 | 0.96 | OR51E2 (0.77) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Glycine SCHEMBL996872 | 0.92 | — | — | |
| Glycine SCHEMBL30677914 | 0.92 | OR51E2 (0.83) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Glycine SCHEMBL391786 | 0.91 | GLRA1 (1.00) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Glycine SCHEMBL93765 | 0.91 | GLRA1 (1.00) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Glycine SCHEMBL3640989 | 0.91 | GLRA1 (1.00) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Glycine SCHEMBL2116443 | 0.91 | — | — | |
| Glycine SCHEMBL6675874 | 0.91 | GLRA1 (1.00) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Glycine SCHEMBL6163 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027687-B | Soybean protein isolate-vanillin compound ultrasonic modified material and preparation method thereof | 吉林农业大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-118027687-A | Soybean protein isolate-vanillin compound ultrasonic modified material and preparation method thereof | 吉林农业大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-117356617-A | Compound preservative for refrigerated weever slices and comprehensive preservation and quality guarantee method thereof | 武汉轻工大学 | 2024-01-09 | — | — | CN | disclosed |
| CN-116869138-A | Method for improving quality of pork texture of braised pork in soy sauce by pressure cooker variable-temperature and variable-pressure cooking | 江南大学 | 2023-10-13 | — | — | CN | disclosed |