Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455772 | 0.89 | CYP1A2 (0.65) | CYP1A2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15974606 | 0.86 | TSHR (0.48) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL4731418 | 0.83 | CYP1A2 (0.50) | CYP1A2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28039727 | 0.80 | GPR84 (0.52) | CYP1A2HDAC11TSHRLMNAKMT2A | |
| SCHEMBL16558618 | 0.79 | CYP1A2 (0.60) | CYP1A2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL35180 | 0.75 | — | — | |
| SCHEMBL3083750 | 0.75 | CYP1A2 (0.50) | CYP1A2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11856427 | 0.75 | TSHR (0.48) | CYP1A2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3683345 | 0.74 | CYP1A2 (0.48) | CYP1A2TSHRLMNAKMT2AHSD17B10 | |
| Propionic Acid SCHEMBL19253781 | 0.73 | FFAR3 (0.48) | CYP1A2HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132235-A1 | PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS | Commonwealth Scientific and Industrial Research Organisation (AU) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008103144-A1 | PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-08-28 | — | — | WO | disclosed |