SCHEMBL3683345

SCHEMBL3683345

N#CCSC(=S)SCCC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
TSHR P16473 1/20 0.39
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4455772 0.83 CYP1A2 (0.65) CYP1A2TSHRLMNAKMT2AHSD17B10
SCHEMBL3762190 0.82 AKR1B1 (0.34) CYP1A2TSHRKMT2AHSD17B10TDP1
SCHEMBL3762188 0.77 TSHR (0.50) TSHRHSD17B10
SCHEMBL16558618 0.74 CYP1A2 (0.60) CYP1A2TSHRLMNAKMT2AHSD17B10
SCHEMBL4445906 0.74 CYP1A2 (0.54) CYP1A2TSHRLMNAKMT2AHSD17B10
SCHEMBL16558626 0.73 CYP1A2 (0.44) CYP1A2TSHRLMNAKMT2AHSD17B10
SCHEMBL6968542 0.73
SCHEMBL28039727 0.72 GPR84 (0.52) CYP1A2TSHRLMNAKMT2AHSD17B10
SCHEMBL4731418 0.71 CYP1A2 (0.50) CYP1A2TSHRKMT2AHSD17B10TDP1
SCHEMBL11856427 0.70 TSHR (0.48) CYP1A2TSHRLMNAKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8569441-B2 Process for transforming the end groups of polymers COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2013-10-29 US claimed
US-20100137548-A1 PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-06-03 US claimed
EP-2132235-A1 PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS Commonwealth Scientific and Industrial Research Organisation (AU) 2009-12-16 EP claimed
WO-2008103144-A1 PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-08-28 WO claimed
US-8569441-B2 Process for transforming the end groups of polymers COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2013-10-29 US disclosed
US-8569441-B2 Process for transforming the end groups of polymers COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2013-10-29 US disclosed
US-8569441-B2 Process for transforming the end groups of polymers COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2013-10-29 US disclosed
US-20100137548-A1 PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-06-03 US disclosed
US-20100137548-A1 PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-06-03 US disclosed
US-20100137548-A1 PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-06-03 US disclosed
EP-2132235-A1 PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS Commonwealth Scientific and Industrial Research Organisation (AU) 2009-12-16 EP disclosed
WO-2008103144-A1 PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-08-28 WO disclosed
WO-2008103144-A1 PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-08-28 WO disclosed