SCHEMBL444616

SCHEMBL444616

CC1=CC(=O)CC(C)(C)C1=O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
NR2F2 P24468 1/20 0.38
ALDH1A1 P00352 8/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 1/20 0.36
HPGD P15428 5/20 0.34
MAPT P10636 3/20 0.34
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
APEX1 P27695 1/20 0.33
LMNA P02545 2/20 0.32
KDM4E B2RXH2 2/20 0.32
HIF1A Q16665 1/20 0.32
TSHR P16473 1/20 0.32
PKM P14618 1/20 0.32
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8405944 0.77 ALDH1A1 (0.34) L3MBTL1ALDH1A1NPC1RAB9AHPGD
SCHEMBL11607730 0.77 ALDH1A1 (0.34) L3MBTL1ALDH1A1NPC1RAB9AHPGD
SCHEMBL11244350 0.75
SCHEMBL9314642 0.74 HIF1A (0.34) L3MBTL1ALDH1A1NPC1RAB9AHPGD
SCHEMBL10528485 0.74 L3MBTL1 (0.45) L3MBTL1NR2F2ALDH1A1NPC1RAB9A
SCHEMBL9001293 0.73 ALDH1A1 (0.33) L3MBTL1ALDH1A1NPC1RAB9AHPGD
SCHEMBL31522375 0.73 ALDH1A1 (0.35) L3MBTL1ALDH1A1NPC1RAB9AHPGD
SCHEMBL9691487 0.71 L3MBTL1 (0.33) L3MBTL1ALDH1A1KMT2AMEN1HIF1A
SCHEMBL9693145 0.71 L3MBTL1 (0.33) L3MBTL1ALDH1A1KMT2AMEN1HIF1A
SCHEMBL7457357 0.71 L3MBTL1 (0.36) L3MBTL1NPC1RAB9ALMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1633 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124216-A1 METHOD FOR INCREASING POLLINATION IN CROPS SUSCEPTIBLE TO POLLINATION OF INVERTEBRATES OF THE APIDEAE FAMILIES APIX BIOSCIENCES N.V. (BE) 2026-05-07 US claimed
US-20250344991-A1 COMPOSITIONS AND METHODS FOR A UNIVERSAL CLINICAL TEST FOR OLFACTORY DYSFUNCTION UNIV ROCKEFELLER (US) 2025-11-13 US claimed
EP-3648613-B1 COMPOSITIONS AND METHODS FOR A UNIVERSAL CLINICAL TEST FOR OLFACTORY DYSFUNCTION UNIV ROCKEFELLER (US) 2025-09-24 EP claimed
EP-4444108-B1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-09-10 EP claimed
CN-116621682-B Preparation method of 4-oxo-isophorone 山东新和成精化科技有限公司 2025-06-24 CN claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
CN-116713034-B Organic photocatalyst, preparation method and method for preparing oxo-isophorone by using organic photocatalyst 万华化学集团股份有限公司 2025-06-03 CN claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-115850063-B Preparation method of 2,3, 5-trimethylhydroquinone diester 万华化学集团股份有限公司 2025-05-13 CN claimed
CN-119924491-A Flavoring composition with balanced taste characteristics 西姆莱斯有限公司 2025-05-06 CN claimed
US-4157352-A Process for the manufacture of a cyclopentenedione HOFFMANN-LA ROCHE INC. (US) 1979-06-05 US claimed
EP-0000885-A1 Process for the preparation of a cyclopentene dione F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1979-03-07 EP claimed
US-4126641-A KETAL, HYDROLYSIS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-11-21 US claimed
US-4092361-A OXIDATION OF BETA-ISOPHORONE, CARBON BLACK AS CATALYST RHONE-POULENC INDUSTRIES (FR) 1978-05-30 US claimed
US-4026947-A CHELATE CATALYSTS OF COBALT OR MANGANESE RHONE-POULENC INDUSTRIES (FR) 1977-05-31 US claimed
US-4026948-A OXIDATION CATALYST; ACETATE OR ACETYLACETONATE OF A TRANSITION METAL FIRMENICH S.A. (CH) 1977-05-31 US claimed
US-4010205-A 2,2,6-TRIMETHYLCYCLOHEX-5-ENE-1,4-DIONE BY OXIDIZING 3,3,5-TRIMETHYLCYCLOHEX-4-EN-1-ONE FIRMENICH S.A. (CH) 1977-03-01 US claimed
US-3989857-A Flavoring phenol or phenol derivative containing food or feed with cycloaliphatic derivatives FIRMENICH S.A. (CH) 1976-11-02 US claimed
US-3944620-A OXIDATION OF 3,5,5-TRIMETHYL-CYCLOHEX-2-EN-1-ONE TO 2,2,6-TRIMETHYL-CYCLOHEX-5-EN-1,4-DIONE FIRMENICH S.A. (CH) 1976-03-16 US claimed
US-3931327-A Process for the preparation of a diketone derivative FIRMENICH SA (CH) 1976-01-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124216-A1 METHOD FOR INCREASING POLLINATION IN CROPS SUSCEPTIBLE TO POLLINATION OF INVERTEBRATES OF THE APIDEAE FAMILIES MELK, TOMM70, MYBBP1A L3MBTL1 718/4885NR2F2 3549/4885ALDH1A1 4866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.