Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | KRAS | P01116 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187233 | 0.84 | TNFRSF1A (0.62) | ABCB1ABCG2ALDH1A1LMNAMAPT | |
| SCHEMBL7187236 | 0.84 | TNFRSF1A (0.62) | ABCB1ABCG2ALDH1A1LMNAMAPT | |
| SCHEMBL3649269 | 0.84 | TNFRSF1A (0.52) | ABCB1ABCG2ALDH1A1LMNAMAPT | |
| SCHEMBL18593318 | 0.79 | ABCB1 (1.00) | ABCB1ABCG2ALDH1A1LMNAMAPT | |
| SCHEMBL7191889 | 0.78 | PDE4A (0.60) | ABCB1ABCG2ALDH1A1LMNAMAPT | |
| SCHEMBL7191886 | 0.78 | PDE4A (0.60) | ABCB1ABCG2ALDH1A1LMNAMAPT | |
| SCHEMBL31167606 | 0.78 | ABCG2 (0.77) | ABCB1ABCG2MAOBARCYP3A4 | |
| SCHEMBL18593317 | 0.77 | ABCG2 (0.66) | ABCB1ABCG2MAOBARCYP3A4 | |
| SCHEMBL29211623 | 0.77 | ABCG2 (0.66) | ABCB1ABCG2ALDH1A1LMNAMAPT | |
| SCHEMBL1764951 | 0.77 | NFE2L2 (0.70) | ABCG2ALDH1A1LMNAMAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090182058-A1 | Novel Chalcone Derivatives With Antimitotic Activity | UNIVERSITE JOSEPH FOURIER GRENOBLE I (FR) | 2009-07-16 | — | — | US | claimed |
| US-20090182058-A1 | Novel Chalcone Derivatives With Antimitotic Activity | UNIVERSITE JOSEPH FOURIER GRENOBLE I (FR) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182058-A1 | Novel Chalcone Derivatives With Antimitotic Activity | ABCE1, CCNE1, FOXM1 | ABCB1 122/4885ABCG2 38/4885ALDH1A1 3972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.