Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 2/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453538 | 0.98 | LMNA (0.62) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL4456936 | 0.98 | LMNA (0.62) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9936149 | 0.95 | LMNA (0.52) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL4113755 | 0.86 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL14856642 | 0.84 | LMNA (0.58) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL17242078 | 0.82 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL11037005 | 0.81 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL2700361 | 0.81 | LMNA (0.68) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL4740185 | 0.81 | LMNA (0.68) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL1246202 | 0.79 | MAPT (0.67) | LMNAMAPTMAPK1ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132246-A1 | METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT | Sika Technology AG (CH) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008116927-A1 | METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | disclosed |