Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 2/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453538 | 1.00 | LMNA (0.62) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL4446358 | 0.98 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9936149 | 0.93 | LMNA (0.52) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL4113755 | 0.84 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL17242078 | 0.84 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL11037005 | 0.83 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL14856642 | 0.83 | LMNA (0.58) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9768573 | 0.82 | LMNA (0.71) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL13227574 | 0.82 | LMNA (0.71) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL3503119 | 0.82 | LMNA (0.71) | LMNAMAPTMAPK1ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021391-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION WITH HIGH EARLY STRENGTH | Sika Technology AG (CH) | 2009-02-11 | — | — | EP | disclosed |
| EP-1996635-A1 | MOISTURE-CURING POLYURETHANE COMPOSITION WITH GOOD LOW-TEMPERATURE PERFORMANCE | Sika Technology AG (CH) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007128824-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION WITH HIGH EARLY STRENGTH | SIKA TECHNOLOGY AG (CH) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007104761-A1 | MOISTURE-CURING POLYURETHANE COMPOSITION WITH GOOD LOW-TEMPERATURE PERFORMANCE | SIKA TECHNOLOGY AG (CH) | 2007-09-20 | — | — | WO | disclosed |