Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4446358 | 0.95 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL4453538 | 0.93 | LMNA (0.62) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL4456936 | 0.93 | LMNA (0.62) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL2982658 | 0.80 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1FAAH | |
| SCHEMBL9451858 | 0.80 | MEN1 (0.34) | LMNAALDH1A1FAAHCNR1CNR2 | |
| SCHEMBL2988368 | 0.80 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1FAAH | |
| SCHEMBL2689971 | 0.80 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1FAAH | |
| SCHEMBL4113755 | 0.80 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL14856642 | 0.79 | LMNA (0.58) | LMNAMAPTMAPK1ALDH1A1FAAH | |
| SCHEMBL9011176 | 0.79 | MAPT (0.58) | LMNAMAPTMAPK1ALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651875-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080264-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | disclosed |