SCHEMBL444658

SCHEMBL444658

CCC=C(O)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL228542 1.00
SCHEMBL9773626 0.83 TDP1 (0.31)
SCHEMBL3221896 0.79
SCHEMBL367396 0.79
SCHEMBL3652169 0.79 ALDH1A1 (0.38)
SCHEMBL5705571 0.78 ZDHHC20 (0.33)
SCHEMBL16660 0.77
SCHEMBL419451 0.77
SCHEMBL5831469 0.75 EP300 (0.47)
SCHEMBL1255448 0.75 EP300 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2760917-A1 SILICONE HYDROGELS HAVING IMPROVED CURING SPEED AND OTHER PROPERTIES Johnson & Johnson Vision Care Inc. (US) 2014-08-06 EP claimed
WO-2013048990-A1 SILICONE HYDROGELS HAVING IMPROVED CURING SPEED AND OTHER PROPERTIES JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-04-04 WO claimed
US-11834547-B2 Ophthalmic devices derived from grafted polymeric networks and processes for their preparation and use JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-12-05 US disclosed
CN-109666121-B Hybrid dynamic cross-linked polymer and application thereof 厦门逍扬运动科技有限公司 2023-09-22 CN disclosed
EP-4204513-A1 METHOD FOR CONTROLLING THE MIGRATION OF FORMATION FINES Poweltec (FR) 2023-07-05 EP disclosed
WO-2022043055-A1 METHOD FOR CONTROLLING THE MIGRATION OF FORMATION FINES POWELTEC (FR) 2022-03-03 WO disclosed
US-20210179766-A1 OPHTHALMIC DEVICES DERIVED FROM GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE JOHNSON & JOHNSON VISION CARE (US) 2021-06-17 US disclosed
EP-3759148-A1 POLYMER PARTICLES WITH A GRADIENT COMPOSITION AND METHODS OF PRODUCTION THEREOF Waters Technologies Corporation (US) 2021-01-06 EP disclosed
EP-3494168-A1 POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE Johnson & Johnson Vision Care Inc. (US) 2019-06-12 EP disclosed
WO-2018026822-A1 POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE JOHNSON & JOHNSON VISION CARE, INC. (US) 2018-02-08 WO disclosed
EP-3277845-A1 BEADS FOR NUCLEIC ACID SEQUENCING Genapsys Inc. (US) 2018-02-07 EP disclosed
US-7919117-B2 Drug delivery of fesoterodine (fumarate) through the skin in a dosage ofo.r-20 mg per day and is provided in a polymer matrix for uniform release;contact adhesives; sel-adhesives; impermeable backing; flatness; geratrics;drug delivery; side effect reduction UCB PHARMA GMBH (DE) 2011-04-05 US disclosed
WO-2010055162-A1 ENANTIOSELECTIVE SYNTHESIS OF γ-AMINO-α,β-UNSATURATED CARBOXYLIC ACID DERIVATIVES NOVARTIS AG (CH) 2010-05-20 WO disclosed
US-7670621-B2 Transdermal administration of (R)-3,3-diphenylpropylamin-monoesters SCHWARZ PHARMA AG (DE) 2010-03-02 US disclosed
US-20090274761-A1 TRANSDERMAL DELIVERY OF (R)-3,3-DIPHENYLPROPYLAMIN-MONOESTERN SCHWARZ PHARMA AG (DE) 2009-11-05 US disclosed
US-20090012159-A1 HIGH PURITY BASES OF 3,3-DIPHENYLPROPYLAMINO MONOESTERS UCB PHARMA GMBH (DE) 2009-01-08 US disclosed
US-20060029673-A1 Transdermal administration of (r)-3,3-diphenylpropylamin-monoesters SCHWARZ PHARMA AG (DE) 2006-02-09 US disclosed
US-20060014832-A1 Highly pure bases of 3,3-dipheyl propylamine monoesters SCHWARZ PHARMA AG (DE) 2006-01-19 US disclosed
US-4676911-A ACRYLIC AMIDE SULFATE, ACRYLIC ACID COPOLYMERS NALCO CHEMICAL COMPANY (US) 1987-06-30 US disclosed
US-3954863-A Synthesis, polymerization and quaternization of N-substituted acrylamidines UNION CARBIDE CORPORATION (US) 1976-05-04 US disclosed