Triamcinolone

Triamcinolone

SCHEMBL4447

C[C@]12C=CC(=O)C=C1CC[C@H]1[C@@H]3C[C@@H](O)[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@]12F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

NR3C1

The experimentally established mechanism targets of Triamcinolone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 known ✓ P04150 9/20 1.00
HIF1A Q16665 8/20 1.00
CYP3A4 P08684 7/20 1.00
LMNA P02545 5/20 1.00
HSD17B10 Q99714 4/20 1.00
PGR P06401 4/20 1.00
NFKB1 P19838 3/20 1.00
CYP2C9 P11712 3/20 1.00
PMP22 Q01453 2/20 1.00
CYP2J2 P51589 1/20 1.00
BLM P54132 1/20 1.00
CYP2C19 P33261 1/20 1.00
TSHR P16473 2/20 0.86
AR P10275 2/20 0.86
MEN1 O00255 1/20 0.86
CYP2D6 P10635 1/20 0.86
KMT2A Q03164 1/20 0.86
APEX1 P27695 1/20 0.86
NPSR1 Q6W5P4 1/20 0.86
IKBKB O14920 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triamcinolone SCHEMBL1884154 1.00 NR3C1 (1.00) NR3C1HIF1ACYP3A4LMNAHSD17B10
Triamcinolone SCHEMBL9863653 1.00 NR3C1 (1.00) NR3C1HIF1ACYP3A4LMNAHSD17B10
Triamcinolone SCHEMBL601461 1.00 NR3C1 (1.00) NR3C1HIF1ACYP3A4LMNAHSD17B10
Triamcinolone SCHEMBL1502196 1.00 NR3C1 (1.00) NR3C1HIF1ACYP3A4LMNAHSD17B10
Triamcinolone SCHEMBL14373318 1.00 NR3C1 (1.00) NR3C1HIF1ACYP3A4LMNAHSD17B10
Triamcinolone SCHEMBL8813577 1.00 NR3C1 (1.00) NR3C1HIF1ACYP3A4LMNAHSD17B10
Triamcinolone SCHEMBL24622562 1.00 NR3C1 (1.00) NR3C1HIF1ACYP3A4LMNAHSD17B10
Triamcinolone SCHEMBL601462 1.00 NR3C1 (1.00) NR3C1HIF1ACYP3A4LMNAHSD17B10
Triamcinolone SCHEMBL570639 1.00 NR3C1 (1.00) NR3C1HIF1ACYP3A4LMNAHSD17B10
Triamcinolone SCHEMBL22962813 1.00 NR3C1 (1.00) NR3C1HIF1ACYP3A4LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 89525 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747263-A1 LIPID NANOPARTICLES AND USES THEREOF University of Connecticut (US) 2026-05-27 EP claimed
EP-4746852-A1 LIPID AGGREGATES FOR INTRAARTICULAR ADMINISTRATION Universität Bern (CH) 2026-05-27 EP claimed
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
US-20260137656-A1 METHODS AND COMPOSITIONS FOR TREATING GLUCOCORTICOID EXCESS SPARROW PHARMACEUTICALS INC (US) 2026-05-21 US claimed
US-20260137558-A1 OPHTHALMIC DEVICE Able Tx Ltd. (IL) 2026-05-21 US claimed
US-20260137657-A1 METHODS AND COMPOSITIONS FOR TREATING GLUCOCORTICOID EXCESS SPARROW PHARMACEUTICALS INC (US) 2026-05-21 US claimed
EP-4743103-A1 COMBINATION OF A HB-EGF INHIBITOR AND A CORTICOSTEROID AGENT FOR THE TREATMENT OF KIDNEY DISEASES ASSOCIATED WITH ACTIVATION OF THE HB-EGF/EGFR PATHWAY Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2026-05-20 EP claimed
EP-4745155-A1 POWDER CONTAINING PARTICLES OF GELATIN DERIVATIVE AND APPLICATION OF SAME IN MEDICAL TREATMENT National Institute for Materials Science (JP) 2026-05-20 EP claimed
CN-119793345-B Ultra-smooth microcapsule, composite material thereof and preparation method of ultra-smooth microcapsule and composite material 清华大学 2026-05-19 CN claimed
CN-122056884-A Methods of treating pancreatic cancer 坎莫森特里克斯公司 2026-05-19 CN claimed
EP-0005476-A2 Process for preparing human interferon Dr. Karl Thomae GmbH (DE) 1979-11-28 EP claimed
US-4131652-A Medicinal skin cream for psoriasis and method DELUCCIA CHARLES R 1978-12-26 US claimed
US-4130643-A STEROID, SUCROSE ESTER, SULFOXIDE THE PROCTER & GAMBLE COMPANY (US) 1978-12-19 US claimed
US-4113680-A Method for preparing 17 α-ester-21-halo pregnanes TAISHO PHARMACEUTICAL CO., LTD. (JP) 1978-09-12 US claimed
US-4112073-A Medicinal composition comprising adrenal cortical hormone and thyroid stimulating hormone releasing hormone TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1978-09-05 US claimed
US-4060606-A 16-SULFIDES OR SULFOXIDES, STEROIDS, ANTIBACTERIAL LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) 1977-11-29 US claimed
US-4014987-A VAGINAL DEVICE; USING A HYDROPHOBIC POLYCARBOXYLIC ACID AS DRUG RELEASE RATE CONTROLLER ALZA CORPORATION (US) 1977-03-29 US claimed
US-4011317-A STEROID DERIVATIVES RORER ITALIANA S.P.A. (IT) 1977-03-08 US claimed
US-4008321-A STEROID TOKO YAKUHIN KOGYO KABUSHIKI KAISHA (JA) 1977-02-15 US claimed
US-3962414-A Structured bioerodible drug delivery device ALZA CORPORATION (US) 1976-06-08 US claimed