Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL4443631 | 1.00 | CA1 (0.44) | CA1BBOX1CA2LSSGPR84 | |
| SCHEMBL6882306 | 0.88 | CA1 (0.43) | CA1BBOX1CA2LSSGPR84 | |
| Cadaverine Tartrate SCHEMBL8435538 | 0.85 | DNM1 (0.58) | CA1CA2LSSGPR84FFAR1 | |
| Cadaverine Tartrate SCHEMBL8437267 | 0.85 | DNM1 (0.58) | CA1CA2LSSGPR84FFAR1 | |
| Cadaverine Tartrate SCHEMBL28551435 | 0.85 | CA2 (0.44) | CA1BBOX1CA2LSSGPR84 | |
| Cetrimonium SCHEMBL5533041 | 0.85 | DNM1 (0.58) | CA1CA2LSSGPR84FFAR1 | |
| Cadaverine Tartrate SCHEMBL2204104 | 0.84 | HTT (0.56) | CA1CA2LSSGPR84FFAR1 | |
| Cadaverine Tartrate SCHEMBL2205954 | 0.84 | HTT (0.56) | CA1CA2LSSGPR84FFAR1 | |
| Cadaverine Tartrate SCHEMBL9094501 | 0.83 | SLC22A1 (0.52) | CA2GPR84FFAR1DNM1 | |
| SCHEMBL3859153 | 0.81 | CA1 (0.47) | CA1BBOX1CA2LSSDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2073782-A2 | DENTAL COMPOSITIONS INCLUDING ORGANOGELATORS, PRODUCTS, AND METHODS | 3M Innovative Properties Company (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008033911-A2 | DENTAL COMPOSITIONS INCLUDING ORGANOGELATORS, PRODUCTS, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-03-20 | — | — | WO | disclosed |