Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903812 | 0.79 | HMGCR (0.48) | LMNAFDPSALDH1A1TDP1HMGCR | |
| SCHEMBL27486220 | 0.74 | LMNA (0.39) | LMNAFDPSALDH1A1TDP1HMGCR | |
| SCHEMBL8350480 | 0.73 | PPARD (0.41) | LMNAALDH1A1TDP1 | |
| SCHEMBL2466614 | 0.73 | ALDH1A1 (0.39) | LMNAFDPSALDH1A1CHRM1TBXA2R | |
| SCHEMBL31603924 | 0.73 | LMNA (0.35) | LMNAFDPSHMGCRCHRM1TBXA2R | |
| SCHEMBL2238467 | 0.73 | TSHR (0.40) | LMNAFDPS | |
| SCHEMBL8350477 | 0.73 | MGAM (0.32) | ALDH1A1 | |
| SCHEMBL5463500 | 0.71 | LMNA (0.47) | LMNAFDPSGRM4PGK1PGK2 | |
| SCHEMBL7193996 | 0.70 | LMNA (0.32) | LMNAFDPS | |
| SCHEMBL10968757 | 0.70 | PPARD (0.38) | LMNAALDH1A1TDP1HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044944-A1 | NOOTROPIC MEDICINAL AGENT | Rasnetsov, Lev Davidovich (RU) | 2009-04-08 | — | — | EP | disclosed |
| US-5861107-A | ESTER INTERCHANGE OF 1,3-PROPANEDIOL COMPOUNDS WITH CARBONIC ACID ESTERS; DISTILLATIVE DEPOLYMERIZATION; CATALYSIS WITH TITANIUM OR ZIRCONIUM COMPOUND; PHOSPHORUS OR SULFUR COMPOUND STABILIZER | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | disclosed |
| EP-0816354-A1 | Process for preparing and stabilisation of aliphatic six-membered cyclic carbonates | BAYER AG (DE) | 1998-01-07 | — | — | EP | disclosed |
| WO-1985002770-A1 | ANTIACIDOTIC MEDICINAL AGENT | INSTITUT ORGANICHESKOI I FIZICHESKOI KHIMII IMENI (SU) | 1985-07-04 | — | — | WO | disclosed |