SCHEMBL8350477

SCHEMBL8350477

COP(=O)(OC)C(C)(C)CC(C)=O

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
ALDH1A1 P00352 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10968757 0.78 PPARD (0.38) ALDH1A1
SCHEMBL4448059 0.73 LMNA (0.39) ALDH1A1
SCHEMBL5665801 0.69 L3MBTL1 (0.32) GAAALDH1A1
SCHEMBL8350480 0.68 PPARD (0.41) ALDH1A1
SCHEMBL6917293 0.67 GAA (0.31) GAA
SCHEMBL28544159 0.66 GABRR1 (0.34)
SCHEMBL28519711 0.65 GAA (0.38) MGAMGAASIMGAM2ALDH1A1
Methoxymethane SCHEMBL991927 0.65 GAA (0.38) MGAMGAASIMGAM2ALDH1A1
SCHEMBL557272 0.65
SCHEMBL7445196 0.64 LMNA (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5861107-A ESTER INTERCHANGE OF 1,3-PROPANEDIOL COMPOUNDS WITH CARBONIC ACID ESTERS; DISTILLATIVE DEPOLYMERIZATION; CATALYSIS WITH TITANIUM OR ZIRCONIUM COMPOUND; PHOSPHORUS OR SULFUR COMPOUND STABILIZER BAYER AKTIENGESELLSCHAFT (DE) 1999-01-19 US disclosed
EP-0816354-A1 Process for preparing and stabilisation of aliphatic six-membered cyclic carbonates BAYER AG (DE) 1998-01-07 EP disclosed
US-4113669-A Polymers flameproofed with 1,2-oxaphospholanes CIBA-GEIGY CORPORATION (US) 1978-09-12 US disclosed
US-4105630-A EPOXY RESINS FLAMEPROOFED WITH 1,2-OXAPHOSPHOLANES CIBA-GEIGY CORPORATION (US) 1978-08-08 US disclosed
US-4045518-A FLAMEPROOFING AGENTS CIBA-GEIGY CORPORATION (US) 1977-08-30 US disclosed
US-4042649-A FIREPROOFING EPOXY RESINS CIBA-GEIGY CORPORATION (US) 1977-08-16 US disclosed