SCHEMBL4448189

SCHEMBL4448189

C[Si](C)(c1cccc2c1C=C1C2=Nc2ccccc21)c1cccc2c1=CC1=c3ccccc3=NC=21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4448185 0.81 ABCG2 (0.38)
SCHEMBL3507971 0.80
SCHEMBL28246158 0.65 ABCG2 (0.40)
SCHEMBL4313632 0.62 ABCG2 (0.40)
SCHEMBL1899426 0.62 ABCG2 (0.40)
SCHEMBL1820364 0.62 ABCG2 (0.40)
Hydrochloric Acid SCHEMBL4458472 0.61 ABCG2 (0.39)
Hydrochloric Acid SCHEMBL4458471 0.61 ABCG2 (0.39)
SCHEMBL9844740 0.60 ABCG2 (0.35)
SCHEMBL2955393 0.59 ABCG2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567561-B1 BIMETALLIC INDENOINDOLYL CATALYSTS EQUISTAR CHEM LP (US) 2009-05-27 EP disclosed
EP-1567561-A1 BIMETALLIC INDENOINDOLYL CATALYSTS Equistar Chemicals, LP (US) 2005-08-31 EP disclosed
US-6841500-B2 Bimetallic indenoindolyl catalysts EQUISTAR CHEMICALS, LP (US) 2005-01-11 US disclosed
WO-2004050718-A1 BIMETALLIC INDENOINDOLYL CATALYSTS EQUISTAR CHEMICALS, LP (US) 2004-06-17 WO disclosed
US-20040106514-A1 Bimetallic indenoindolyl catalysts EQUISTAR CHEMICALS, LP 2004-06-03 US disclosed