Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 3/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.46 |
| ▸ | G6PD | P11413 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939193 | 0.85 | SHBG (0.64) | CYP17A1TBXAS1SRD5A2SHBGSERPINA6 | |
| SCHEMBL3366382 | 0.85 | SHBG (0.64) | CYP17A1TBXAS1SRD5A2SHBGSERPINA6 | |
| SCHEMBL14149814 | 0.85 | SHBG (0.64) | CYP17A1TBXAS1SRD5A2SHBGSERPINA6 | |
| SCHEMBL12310691 | 0.85 | SHBG (0.64) | CYP17A1TBXAS1SRD5A2SHBGSERPINA6 | |
| SCHEMBL336035 | 0.85 | SHBG (0.64) | CYP17A1TBXAS1SRD5A2SHBGSERPINA6 | |
| SCHEMBL23155091 | 0.85 | SHBG (0.64) | CYP17A1TBXAS1SRD5A2SHBGSERPINA6 | |
| SCHEMBL11970666 | 0.85 | SHBG (0.64) | CYP17A1TBXAS1SRD5A2SHBGSERPINA6 | |
| SCHEMBL4617662 | 0.85 | L3MBTL1 (0.62) | CYP17A1TBXAS1SRD5A2SHBGSERPINA6 | |
| SCHEMBL13461623 | 0.85 | SHBG (0.64) | CYP17A1TBXAS1SRD5A2SHBGSERPINA6 | |
| SCHEMBL13076860 | 0.85 | SHBG (0.64) | CYP17A1TBXAS1SRD5A2SHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2012773-A2 | DRUGS AND USES | Hollis-Eden Pharmaceuticals Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008039566-A2 | DRUGS AND USES | HOLLIS-EDEN PHARMACEUTICALS, INC. (US) | 2008-04-03 | — | — | WO | disclosed |
| WO-1997036596-A9 | STEROIDS AS NEUROCHEMICAL INITIATORS OF CHANGE IN HUMAN BLOOD LEVELS OF LH OR FSH | — | 1997-12-04 | — | — | WO | disclosed |