Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 4/20 | 0.64 |
| ▸ | G6PD | P11413 | 3/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | GUSB | P08236 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CYP17A1 | P05093 | 9/20 | 0.64 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18925198 | 1.00 | SHBG (0.64) | SHBGG6PDSERPINA6ESR1AR | |
| SCHEMBL14149814 | 1.00 | SHBG (0.64) | SHBGG6PDSERPINA6ESR1AR | |
| SCHEMBL3366382 | 1.00 | SHBG (0.64) | SHBGG6PDSERPINA6ESR1AR | |
| SCHEMBL336035 | 1.00 | SHBG (0.64) | SHBGG6PDSERPINA6ESR1AR | |
| SCHEMBL12310691 | 1.00 | SHBG (0.64) | SHBGG6PDSERPINA6ESR1AR | |
| SCHEMBL23155091 | 1.00 | SHBG (0.64) | SHBGG6PDSERPINA6ESR1AR | |
| SCHEMBL13076860 | 1.00 | SHBG (0.64) | SHBGG6PDSERPINA6ESR1AR | |
| SCHEMBL13461623 | 1.00 | SHBG (0.64) | SHBGG6PDSERPINA6ESR1AR | |
| SCHEMBL11970666 | 1.00 | SHBG (0.64) | SHBGG6PDSERPINA6ESR1AR | |
| SCHEMBL336036 | 1.00 | SHBG (0.64) | SHBGG6PDSERPINA6ESR1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220193095-A9 | PHARMACEUTICAL COMPOSITIONS | Shenzhen Pharmacin Co., Ltd. (CN) | 2022-06-23 | — | — | US | disclosed |
| US-20200237784-A1 | PHARMACEUTICAL COMPOSITIONS | SHENZHEN PHARMACIN CO LTD (CN) | 2020-07-30 | — | — | US | disclosed |
| EP-2667876-A2 | METHODS AND COMPOUNDS FOR PREPARING 3ALPHA-OXYGEN SUBSTITUTED STEROIDS | Harbor BioSciences, Inc. (US) | 2013-12-04 | — | — | EP | disclosed |
| US-20120214987-A1 | METHODS AND COMPOUNDS FOR PREPARING 3ALPHA-OXYGEN SUBSTITUTED STEROIDS | BIOVIE INC. | 2012-08-23 | — | — | US | disclosed |
| WO-2012083090-A2 | METHODS AND COMPOUNDS FOR PREPARING 3ALPHA-OXYGEN SUBSTITUTED STEROIDS | HARBOR BIOSCIENCES, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214987-A1 | METHODS AND COMPOUNDS FOR PREPARING 3ALPHA-OXYGEN SUBSTITUTED STEROIDS | CYP11B1, CYP11A1, HSD17B7 | SHBG 32/4885G6PD 1144/4885SERPINA6 287/4885 |
| US-20220193095-A9 | PHARMACEUTICAL COMPOSITIONS | LIPA, LIPC, MGLL | SHBG 1170/4885G6PD 810/4885SERPINA6 567/4885 |
| US-20200237784-A1 | PHARMACEUTICAL COMPOSITIONS | LIPA, LIPC, MGLL | SHBG 1170/4885G6PD 810/4885SERPINA6 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.