Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101045 | 0.70 | — | — | |
| SCHEMBL444840 | 0.70 | — | — | |
| SCHEMBL2430704 | 0.67 | — | — | |
| SCHEMBL10095122 | 0.67 | — | — | |
| SCHEMBL1169223 | 0.64 | — | — | |
| SCHEMBL23879189 | 0.61 | — | — | |
| Acetic Acid SCHEMBL3392891 | 0.60 | — | — | |
| Acetic Acid SCHEMBL21518270 | 0.57 | — | — | |
| SCHEMBL59794 | 0.56 | — | — | |
| SCHEMBL7207847 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520111-B | Pharmaceutical formulation and method for managing body weight and regulating intestinal microbiota | 塞诺生物科学股份有限公司 | 2023-12-19 | — | — | CN | disclosed |
| US-20230373940-A1 | CARBOXYLIC DIARYLTHIAZEPINEAMINES AND USES THEREOF | KURES, INC. | 2023-11-23 | — | — | US | disclosed |
| US-20230365519-A1 | CARBOXYLIC DIARYLTHIAZEPINEAMINES AND USES THEREOF | KURES, INC. | 2023-11-16 | — | — | US | disclosed |
| US-11787772-B2 | Carboxylic diarythiazepineamines as mixed mu- and delta-opioid receptor agonists | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-10-17 | — | — | US | disclosed |
| US-11510429-B2 | Cyclic ketal compounds having long side chains useful as foam control agents in the manufacture of food and beverage products | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-11-29 | — | — | US | disclosed |
| WO-2022074588-A1 | CARBOXYLIC DIARYLTHIAZEPINEAMINES AND USES THEREFOR | KURES, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
| WO-2022074589-A1 | CARBOXYLIC DIARYLTHIAZEPINEAMINES AND USES THEREFOR | KURES, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
| CN-108135782-B | Dental composition | 登特斯普伊德特雷有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-108135781-B | Dental composition | 登特斯普伊德特雷有限公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-108697587-A | Dental composition | 登特斯普伊德特雷有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108135782-A | Dental composition | 登特斯普伊德特雷有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-108135781-A | Dental composition | 登特斯普伊德特雷有限公司 | 2018-06-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787772-B2 | Carboxylic diarythiazepineamines as mixed mu- and delta-opioid receptor agonists | OPRD1, OPRM1, OPRK1 | LMNA 1921/4885TSHR 510/4885THPO 4543/4885 |
| US-20230373940-A1 | CARBOXYLIC DIARYLTHIAZEPINEAMINES AND USES THEREOF | CDKL5, KMT5A, CDKL1 | LMNA 2827/4885TSHR 4254/4885THPO 4538/4885 |
| US-20230365519-A1 | CARBOXYLIC DIARYLTHIAZEPINEAMINES AND USES THEREOF | CDKL5, CDKL1, H1-5 | LMNA 2227/4885TSHR 2106/4885THPO 4783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.