Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448442 | 1.00 | MRGPRX4 (0.42) | MRGPRX4ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL4448438 | 1.00 | MRGPRX4 (0.42) | MRGPRX4ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL3050403 | 0.90 | MEN1 (0.42) | MRGPRX4ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL3343992 | 0.80 | CA12 (0.50) | ALDH1A1CYP3A4CYP2C9MIFKMT2A | |
| SCHEMBL3343995 | 0.80 | CA12 (0.50) | ALDH1A1CYP3A4CYP2C9MIFKMT2A | |
| SCHEMBL3343985 | 0.80 | CA12 (0.50) | ALDH1A1CYP3A4CYP2C9MIFKMT2A | |
| SCHEMBL3346306 | 0.80 | MEN1 (0.53) | MIFMEN1KMT2ACA12CA1 | |
| SCHEMBL3346312 | 0.80 | MEN1 (0.53) | MIFMEN1KMT2ACA12CA1 | |
| SCHEMBL3346315 | 0.80 | MEN1 (0.53) | MIFMEN1KMT2ACA12CA1 | |
| SCHEMBL3343675 | 0.77 | LMNA (0.48) | ALDH1A1MIFMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531507-B2 | Acylated nonadepsipeptides containing pyridyl alanine residues | AICURIS GMBH & CO. KG (DE) | 2009-05-12 | — | — | US | disclosed |
| US-20060264358-A1 | Acylated nonadepsipeptides II | BAYER HEALTHCARE AG (DE) | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264358-A1 | Acylated nonadepsipeptides II | VIP, LYPLA2, ENPP2 | MRGPRX4 1696/4885ALDH1A1 4570/4885KDM4E 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.