Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 5/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1751110 | 0.85 | NMT1 (0.50) | NMT1CYP3A4TSHRTDP1AHR | |
| SCHEMBL642403 | 0.82 | TSHR (0.47) | CYP3A4TSHRTDP1AHRGABRA1 | |
| SCHEMBL10495441 | 0.81 | ALDH1A1 (0.41) | CYP3A4TSHRAHRKMT2AHPGD | |
| SCHEMBL30494020 | 0.81 | ALDH1A1 (0.41) | CYP3A4TSHRAHRKMT2AHPGD | |
| SCHEMBL8354359 | 0.78 | NMT1 (0.39) | NMT1CYP3A4AHRMAPTMEN1 | |
| SCHEMBL24616492 | 0.77 | CYP3A4 (0.52) | CYP3A4TSHRAHRMAPTALDH1A1 | |
| SCHEMBL17466062 | 0.77 | AGTR1 (0.32) | AHR | |
| SCHEMBL22265085 | 0.77 | CA1 (0.32) | NMT1AHRCA1CA2CA9 | |
| SCHEMBL22265086 | 0.77 | CYP3A4 (0.46) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL31568142 | 0.77 | AHR (0.30) | AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513346-B2 | Flame retardant composition for use in styrenics | CHEMTURA CORPORATION (US) | 2013-08-20 | — | — | US | disclosed |
| US-20120184638-A1 | Flame Retardant Composition for Use in Styrenics | LANXESS SOLUTIONS US INC. | 2012-07-19 | — | — | US | disclosed |
| EP-2115059-A1 | FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS | CHEMTURA CORPORATION (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008127753-A1 | FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS | CHEMTURA CORPORATION (US) | 2008-10-23 | — | — | WO | disclosed |
| US-20080221239-A1 | Flame retardant composition for use in styrenics | RECREATIONAL WATER PRODUCTS, INC. | 2008-09-11 | — | — | US | disclosed |
| EP-0023415-A2 | A method of mounting ventilators, lights and the like in sealed relation to an opening and a preformed sealing material for use in such a method | COLT INTERNATIONAL HOLDINGS A.G. (CH) | 1981-02-04 | — | — | EP | disclosed |
| US-4223172-A | DEHYDROGENATION HALOGENATIVE WITH PALLADIUM-PHOSPHINE COMPLEX CATALYST | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-09-16 | — | — | US | disclosed |