SCHEMBL642403

SCHEMBL642403

Cc1c(Br)cc(Br)cc1Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
CYP3A4 P08684 1/20 0.47
AHR P35869 2/20 0.43
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRB2 P47870 1/20 0.41
PRNP P04156 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
NOD2 Q9HC29 1/20 0.38
ALOX15 P16050 2/20 0.36
ALOX12 P18054 1/20 0.36
ALDH1A1 P00352 4/20 0.35
MAPT P10636 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
MAPK1 P28482 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13086840 0.84 GABRA1 (0.48) TSHRTDP1CYP3A4AHRGABRA1
SCHEMBL5780229 0.84 AHR (0.44) TSHRTDP1CYP3A4AHRGABRA1
SCHEMBL4448671 0.82 NMT1 (0.39) TSHRTDP1CYP3A4AHRGABRA1
SCHEMBL8049737 0.80 CYP3A4 (0.38) TSHRTDP1CYP3A4AHRGABRA1
SCHEMBL28012835 0.80 CYP3A4 (0.38) TSHRTDP1CYP3A4AHRGABRA1
SCHEMBL11136759 0.80 CYP3A4 (0.50) TSHRTDP1CYP3A4AHRGABRA1
SCHEMBL14535949 0.80 CYP3A4 (0.38) TSHRTDP1CYP3A4AHRGABRA1
SCHEMBL28872076 0.80 CYP3A4 (0.38) TSHRTDP1CYP3A4AHRGABRA1
SCHEMBL5778579 0.79 ACHE (0.40) TSHRALDH1A1MAPK1ACP1
SCHEMBL13086842 0.79 APEX1 (0.53) TSHRTDP1CYP3A4NPSR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344586-A Ion covalent organic polymer material and preparation method and application thereof 河北工程大学 2024-07-16 CN claimed
CN-118085313-A Polyion liquid-metal organic framework composite material and preparation method and application thereof 福州大学 2024-05-28 CN claimed
CN-114656525-B RGD cyclic peptide for cancer cell integrin and application thereof in preparation of tumor drugs 合肥师范学院 2024-02-02 CN claimed
CN-117487139-A Covalent organic polymer based on tetrastyrene group, preparation method and application thereof 华南理工大学 2024-02-02 CN claimed
CN-117229197-A Carbazole derivative with AEE characteristic and preparation method and application thereof 辽宁师范大学 2023-12-15 CN claimed
CN-113491959-B Porous polymer film and preparation method and application thereof 国家纳米科学中心 2023-09-22 CN claimed
CN-114656525-A RGD cyclopeptide for cancer cell integrin and application thereof in preparation of tumor drugs 合肥师范学院 2022-06-24 CN claimed
CN-113491959-A Porous polymer film and preparation method and application thereof 国家纳米科学中心 2021-10-12 CN claimed
CN-109575298-B Dendritic polymer and synthesis method and application thereof 复旦大学 2021-08-20 CN claimed
CN-109575297-B Water-soluble monomolecular micelle and preparation method and application thereof 复旦大学 2021-08-20 CN claimed
CN-103657610-B Porous polymer adsorbent for selectively adsorbing carbon dioxide and preparation method thereof NANJING TECH UNIVERSITY (CN) 2016-01-06 CN claimed
CN-103242557-B Elastic hydrophobic material, and synthetic method and application thereof UNIV DALIAN TECH 2015-06-03 CN claimed
US-20140330031-A1 RESIST FOR ELECTRON BEAM AND OPTICAL LITHOGRAPHY COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-11-06 US claimed
US-20140174730-A1 METHOD OF TRACING FLOW OF HYDROCARBON FROM A SUBTERRANEAN RESERVOIR JOHNSON MATTHEY PLC (GB) 2014-06-26 US claimed
CN-103570483-A Preparation method for 3, 5-dithienylethene benzaldehyde UNIV JINAN 2014-02-12 CN claimed
US-8640773-B2 Method of tracing flow of hydrocarbon from a subterranean reservoir JOHNSON MATTHEY PLC (GB) 2014-02-04 US claimed
US-20130277048-A1 METHOD OF TRACING FLOW OF HYDROCARBON FROM A SUBTERRANEAN RESERVOIR TRACERCO LIMITED (GB) 2013-10-24 US claimed
CN-103242557-A Elastic hydrophobic material, and synthetic method and application thereof UNIV DALIAN TECH 2013-08-14 CN claimed
WO-2013084247-A1 RESIST FOR ELECTRON BEAM AND OPTICAL LITHOGRAPHY COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-06-13 WO claimed
US-20130087329-A1 METHOD OF TRACING FLOW OF HYDROCARBON FROM A SUBTERRANEAN RESERVOIR JOHNSON MATHEY PLC (GB) 2013-04-11 US claimed