Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557038 | 0.86 | MAPT (0.65) | MAPTHSD17B10TRPV1KMT2AMEN1 | |
| SCHEMBL4769744 | 0.85 | KMT2A (0.57) | KMT2AMEN1KDM4ELMNANPC1 | |
| SCHEMBL8552292 | 0.83 | SPR (0.56) | TRPV1KMT2AMEN1HPGDLMNA | |
| SCHEMBL31542971 | 0.82 | MAPT (0.56) | MAPTHSD17B10TRPV1KMT2AMEN1 | |
| SCHEMBL21382248 | 0.82 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9AACHE | |
| SCHEMBL10069008 | 0.81 | MAPT (0.55) | MAPTHSD17B10TRPV1KMT2AMEN1 | |
| SCHEMBL8585756 | 0.81 | KMT2A (0.56) | KMT2AMEN1NPC1RAB9AACHE | |
| SCHEMBL5110887 | 0.80 | NPC1 (0.63) | MAPTKMT2AMEN1HPGDLMNA | |
| SCHEMBL7201386 | 0.80 | CNR2 (0.58) | HSD17B10KMT2AKDM4ELMNAHIF1A | |
| SCHEMBL27887140 | 0.80 | KMT2A (0.55) | MAPTKMT2AMEN1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125195-A2 | ANALYSIS KIT COMPRISING AT LEAST TWO MOLECULARLY IMPRINTED POLYMERS AND AT LEAST ONE MARKER, AND METHOD OF ANALYSIS USING SAME | Polyintell (FR) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008132384-A2 | ANALYSIS KIT COMPRISING AT LEAST TWO MOLECULARLY IMPRINTED POLYMERS AND AT LEAST ONE MARKER, AND METHOD OF ANALYSIS USING SAME | POLYINTELL (FR) | 2008-11-06 | — | — | WO | disclosed |