SCHEMBL4448728

SCHEMBL4448728

CCc1cccc(P(=O)(O)OC)c1CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.39
GABRB2 P47870 2/20 0.39
TAAR1 Q96RJ0 2/20 0.35
HTR1A P08908 1/20 0.35
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TP53 P04637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PTPN5 P54829 1/20 0.32
LAP3 P28838 1/20 0.32
ACP3 P15309 1/20 0.32
POLB P06746 2/20 0.31
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 1/20 0.31
NPC1 O15118 1/20 0.31
PTK2B Q14289 1/20 0.31
PLA2G2D Q9UNK4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11039468 0.85 GABRA1 (0.38) GABRA1GABRB2TAAR1HTR1AALDH1A1
SCHEMBL4451735 0.85 ALDH1A1 (0.50) GABRA1GABRB2TAAR1HTR1AALDH1A1
SCHEMBL11373348 0.84 ALDH1A1 (0.41) GABRA1GABRB2ALDH1A1TSHRLAP3
SCHEMBL4448727 0.82 GABRA1 (0.38) GABRA1GABRB2TAAR1HTR1AMEN1
SCHEMBL4462488 0.82 LTB4R (0.34) GABRA1GABRB2ALDH1A1TSHRMEN1
SCHEMBL4451699 0.82 PLA2G2D (0.41) GABRA1GABRB2TAAR1HTR1AALDH1A1
SCHEMBL1537947 0.82 GABRA1 (0.45) GABRA1GABRB2TAAR1HTR1AALDH1A1
SCHEMBL4460850 0.81 ALDH1A1 (0.40) GABRA1GABRB2ALDH1A1TSHRPOLB
SCHEMBL4454579 0.81 SRC (0.44) ALDH1A1LAP3CYP2C19SMN1; SMN2
SCHEMBL4452194 0.80 PLA2G2D (0.48) ALDH1A1PLA2G2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed