Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3329065 | 0.83 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL4442347 | 0.83 | LMNA (0.33) | KCNH2 | |
| SCHEMBL19470003 | 0.82 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL3324223 | 0.75 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL4437994 | 0.74 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL3843472 | 0.69 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL3327472 | 0.65 | HSD11B1 (0.37) | — | |
| SCHEMBL3367036 | 0.65 | HTR2C (0.40) | — | |
| SCHEMBL3329038 | 0.65 | LNPEP (0.37) | KCNH2 | |
| SCHEMBL3328621 | 0.65 | HSD11B1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137196-A1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS AS ANTIBACTERIAL AGENTS | Glaxo Group Limited (GB) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008128942-A1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS AS ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |