SCHEMBL444917

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL447665	0.85	HDAC8 (0.54)	HDAC8MEN1KMT2ALMNAERAP1
	SCHEMBL445402	0.85	HDAC8 (0.50)	HDAC8MEN1KMT2AL3MBTL1NPC1
	SCHEMBL443999	0.82	HDAC8 (0.52)	HDAC8MEN1KMT2ALMNANPC1
	SCHEMBL444289	0.81	MEN1 (0.50)	HDAC8MEN1KMT2ADRD4NPC1
	SCHEMBL441672	0.81	HDAC8 (0.48)	HDAC8MEN1KMT2ASRD5A2TAS1R3
	SCHEMBL445526	0.80	CA12 (0.47)	HDAC8MEN1KMT2ASRD5A2LMNA
	SCHEMBL443233	0.74	HDAC8 (0.52)	HDAC8MEN1KMT2ALMNA
	SCHEMBL444884	0.73	HDAC8 (0.55)	HDAC8LMNAERAP1
	SCHEMBL443508	0.72	HDAC8 (0.52)	HDAC8
	SCHEMBL2472548	0.72	MEN1 (0.70)	HDAC8MEN1KMT2ACCR2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.