SCHEMBL441672

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL445526	0.89	CA12 (0.47)	HDAC8TSHRCHRNA7MEN1KMT2A
	SCHEMBL445402	0.87	HDAC8 (0.50)	HDAC8MEN1KMT2APOLBMAPT
	SCHEMBL444289	0.83	MEN1 (0.50)	HDAC8MEN1KMT2ASMYD3
	SCHEMBL443999	0.81	HDAC8 (0.52)	HDAC8TSHRMEN1KMT2AMAPT
	SCHEMBL444917	0.81	HDAC8 (0.52)	HDAC8TAS1R3TAS1R2MEN1KMT2A
	SCHEMBL444812	0.76	HDAC8 (0.61)	HDAC8
	SCHEMBL446231	0.75	KDM4E (0.41)	MEN1KMT2AKDM4EPOLBMAPT
	SCHEMBL443508	0.74	HDAC8 (0.52)	HDAC8MAPT
	SCHEMBL461269	0.73	HDAC8 (0.85)	HDAC8TSHRPYGLPYGMTAS1R3
	SCHEMBL443678	0.69	HDAC8 (0.54)	HDAC8POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.