Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4448322 | 0.98 | TTR (0.50) | TTRSMN1; SMN2ESR1ESR2KMT2A | |
| SCHEMBL4455037 | 0.90 | KMT2A (0.60) | SMN1; SMN2ESR1ESR2KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4452980 | 0.89 | KMT2A (0.59) | SMN1; SMN2ESR1ESR2KMT2AL3MBTL1 | |
| SCHEMBL7837749 | 0.79 | SMN1; SMN2 (0.77) | TTRSMN1; SMN2KMT2AMEN1ATM | |
| SCHEMBL13788913 | 0.77 | KMT2A (0.63) | TTRSMN1; SMN2KMT2AL3MBTL1NSD2 | |
| SCHEMBL25532 | 0.77 | POLB (0.58) | TTRSMN1; SMN2KMT2AMEN1ATM | |
| Hydrochloric Acid SCHEMBL6911530 | 0.76 | ESR1 (0.50) | SMN1; SMN2ESR1ESR2KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6909934 | 0.76 | SMN1; SMN2 (0.46) | TTRSMN1; SMN2ESR1ESR2KMT2A | |
| SCHEMBL4445137 | 0.74 | EDNRA (0.48) | SMN1; SMN2ESR1ESR2KMT2AMEN1 | |
| SCHEMBL7104945 | 0.71 | CYP3A4 (0.57) | SMN1; SMN2KMT2AMEN1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |