Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4452980 | 0.99 | KMT2A (0.59) | KMT2AL3MBTL1ESR1ESR2LMNA | |
| SCHEMBL4449287 | 0.90 | TTR (0.51) | KMT2AL3MBTL1ESR1ESR2LMNA | |
| Hydrochloric Acid SCHEMBL4448322 | 0.89 | TTR (0.50) | KMT2AL3MBTL1ESR1ESR2MAPK1 | |
| Hydrochloric Acid SCHEMBL6909934 | 0.81 | SMN1; SMN2 (0.46) | KMT2AL3MBTL1ESR1ESR2LMNA | |
| SCHEMBL6968140 | 0.77 | ESR2 (0.74) | KMT2AL3MBTL1ESR1ESR2LMNA | |
| SCHEMBL4455025 | 0.77 | KMT2A (0.52) | KMT2AL3MBTL1ESR1ESR2LMNA | |
| SCHEMBL7837749 | 0.77 | SMN1; SMN2 (0.77) | KMT2ALMNAMAPK1MEN1TSHR | |
| SCHEMBL6448521 | 0.75 | KMT2A (0.63) | KMT2AL3MBTL1ESR1ESR2LMNA | |
| SCHEMBL25532 | 0.75 | POLB (0.58) | KMT2ALMNAMEN1TSHRSMN1; SMN2 | |
| SCHEMBL13788913 | 0.74 | KMT2A (0.63) | KMT2AL3MBTL1MEN1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |