Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449309 | 1.00 | ACHE (0.47) | ACHETDP1MEN1KMT2ALMNA | |
| SCHEMBL4449315 | 1.00 | ACHE (0.47) | ACHETDP1MEN1KMT2ALMNA | |
| SCHEMBL11423482 | 0.92 | TSHR (0.48) | ACHETDP1MEN1KMT2ALMNA | |
| SCHEMBL5854039 | 0.83 | ACHE (0.42) | ACHETDP1MEN1KMT2ALMNA | |
| SCHEMBL12346270 | 0.83 | ACHE (0.42) | ACHETDP1MEN1KMT2ALMNA | |
| SCHEMBL19895724 | 0.83 | ACHE (0.42) | ACHETDP1MEN1KMT2ALMNA | |
| SCHEMBL9132881 | 0.76 | SLC5A2 (0.36) | ACHETDP1MEN1KMT2ALMNA | |
| SCHEMBL9802330 | 0.74 | MEN1 (0.38) | ACHETDP1MEN1KMT2ALMNA | |
| SCHEMBL12241573 | 0.74 | SLC5A2 (0.49) | ALDH1A1 | |
| SCHEMBL28453023 | 0.74 | ALDH1A1 (0.38) | ACHETDP1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227635-B2 | Apparatus and method for carrying out multiple reactions | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-8227635-B2 | Apparatus and method for carrying out multiple reactions | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-8227635-B2 | Apparatus and method for carrying out multiple reactions | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-20090299102-A1 | APPARATUS AND METHOD FOR CARRYING OUT MULTIPLE REACTIONS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090299102-A1 | APPARATUS AND METHOD FOR CARRYING OUT MULTIPLE REACTIONS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090299102-A1 | APPARATUS AND METHOD FOR CARRYING OUT MULTIPLE REACTIONS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299102-A1 | APPARATUS AND METHOD FOR CARRYING OUT MULTIPLE REACTIONS | DDO, APEX1, MMAB | ACHE 167/4885TDP1 1273/4885MEN1 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.